Collaboration and License Agreements - Schedule of Collaboration Collaboration revenue (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2024	Dec. 31, 2023	Dec. 31, 2022
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Revenues from contract with customers	$ 74,205	$ 86,180	$ 1,615,797
Profit-sharing amount
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Revenues from contract with customers	9,078	1,536	1,875,147
Profit-sharing amount constrained
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Revenues from contract with customers	(699)	0	(369,678)
Profit-sharing amount previously constrained, released
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Revenues from contract with customers	0	35,730	0
Total collaboration revenue, net
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Revenues from contract with customers	$ 8,379	$ 37,266	$ 1,505,469