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Organization - Additional Information (Details) $ in Thousands		1 Months Ended	12 Months Ended
	Nov. 30, 2020	Nov. 30, 2020 USD ($)	Dec. 31, 2023 USD ($) platform shares	Jun. 30, 2023	Jan. 31, 2023	Dec. 31, 2022 USD ($)
Organization Consolidation And Presentation Of Financial Statements [Line Items]
Number of technology platforms \| platform			2
Aggregate offering price		$ 300,000
Accumulated deficit			$ 237,824			$ (377,237)
Cash, cash equivalents and investments			$ 1,630,000
Encentrio Therapeutics, Inc.
Organization Consolidation And Presentation Of Financial Statements [Line Items]
Equity method ownership percentage				100.00%
Encentrio Therapeutics, Inc.
Organization Consolidation And Presentation Of Financial Statements [Line Items]
Ownership percentage					80.00%
Common Stock \| Sales Agreement
Organization Consolidation And Presentation Of Financial Statements [Line Items]
Issuance of common stock (in shares) \| shares			0
Common Stock \| Sales Agreement \| Maximum
Organization Consolidation And Presentation Of Financial Statements [Line Items]
Percentage of commission rate from sale of shares	3.00%