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Collaboration and License Agreements - Additional Information (Details)
$ in Thousands
3 Months Ended 9 Months Ended 12 Months Ended
Feb. 08, 2023
Sep. 30, 2023
USD ($)
Sep. 30, 2022
USD ($)
Sep. 30, 2023
USD ($)
Sep. 30, 2022
USD ($)
Dec. 31, 2021
USD ($)
program
Dec. 31, 2020
program
Dec. 31, 2022
USD ($)
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                
Number of programs the collaboration to focus on | program             3  
Accrued and other liabilities   $ 146,111   $ 146,111       $ 489,090
Research and development   148,253 $ 114,166 477,756 $ 319,475      
Total unrecognized transaction price   53,207   53,207       $ 53,207
2020 GSK                
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                
Payments to GSK   67,000   340,500        
Accrued and other liabilities   900   900        
Research and development   6,100 10,400 18,600 24,000      
Preliminary Collaboration Agreement | 2020 GSK | Antibody Program                
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                
Percentage of development costs 72.50%              
2021 Collaboration Agreement | 2021 GSK                
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                
Number of separate programs | program           3    
Option exercise fee to be received           $ 300,000    
2021 Collaboration Agreement | 2021 GSK | Maximum                
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                
Pre-defined regulatory milestone payment           $ 200,000    
2021 GSK Collaboration                
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                
Research and development   600 $ 300 1,900 $ 1,300      
Percentage of share development costs           50.00%    
Percentage of share Profit and loss           50.00%    
Total unrecognized transaction price   $ 51,700   $ 51,700