X0306 4 2023-03-01 0 0001706431 Vir Biotechnology, Inc. VIR 0001661908 Sigal Charles Elliott C/O VIR BIOTECHNOLOGY, INC. 499 ILLINOIS STREET, SUITE 500 SAN FRANCISCO CA 94158 1 0 0 0 Common Stock 2023-03-01 4 P 0 2500 22.7262 A 10000 I By Sigal Family Investments, LLC Common Stock 9779 D The purchases reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by Sigal Family Investments, LLC on October 21, 2022, of which the reporting person is the manager. The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $22.595 to $22.94, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the range set forth above. The reporting person disclaims beneficial ownership of these securities except to the extent of his pecuniary interest therein. /s/ Howard Horn, Attorney-in-Fact 2023-03-02