X0306 4 2022-02-17 0 0001706431 Vir Biotechnology, Inc. VIR 0001202102 SCANGOS GEORGE A C/O VIR BIOTECHNOLOGY, INC. 499 ILLINOIS STREET, SUITE 500 SAN FRANCISCO CA 94158 1 1 0 0 President and CEO Common Stock 2022-02-17 4 S 0 10024 31.9308 D 130715 D Common Stock 2022-02-18 4 S 0 17726 30.6501 D 112989 D Common Stock 3598559 I See footnote Common Stock 61660 I See footnote Common Stock 877135 I See footnote Common Stock 61660 I See footnote Common Stock 877135 I See footnote Common Stock 115000 I See footnote Represents the automatic sale of shares to cover the Issuer's tax withholding and remittance obligation in connection with the vesting of restricted stock units. Sales effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on December 24, 2021. The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $30.00 to $30.95 per share, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. The shares are held in the name of George A. Scangos, as Trustee of the Scangos-Wilson Family Trust dated May 12, 2011. The shares are held in the name of the Jennifer Scangos 2018 Exempt Trust, dated August 30, 2018, of which the reporting person and his spouse are Trustees. The shares are held in the name of the Jennifer Scangos 2018 Non-Exempt Trust, dated August 30, 2018, of which the reporting person and his spouse are Trustees. The shares are held in the name of the Katherine Scangos 2018 Exempt Trust, dated August 30, 2018, of which the reporting person and his spouse are Trustees. The shares are held in the name of the Katherine Scangos 2018 Non-Exempt Trust, dated August 30, 2018, of which the reporting person and his spouse are Trustees. The shares are held in the name of the Scangos 2018 Grandchildren's Trust, of which the reporting person and his spouse are Trustees. /s/ Howard Horn, Attorney-in-Fact 2022-02-22