X0306 5 2021-12-31 0 0 0 0001706431 Vir Biotechnology, Inc. VIR 0001202102 SCANGOS GEORGE A C/O VIR BIOTECHNOLOGY, INC. 499 ILLINOIS STREET, SUITE 500 SAN FRANCISCO CA 94158 1 1 0 0 President and CEO Common Stock 2021-02-16 5 G 0 900000 0.00 D 3709559 D Common Stock 2021-04-01 5 G 0 3598559 0.00 D 111000 D Common Stock 2021-04-01 5 G 0 3598559 0.00 A 3598559 I See footnote Common Stock 2021-09-07 5 G 0 1907329 0.00 D 0 I See footnote Common Stock 2021-09-07 5 G 0 61660 0.00 A 61660 I See footnote Common Stock 2021-09-07 5 G 0 877135 0.00 A 877135 I See footnote Common Stock 2021-09-07 5 G 0 61660 0.00 A 61660 I See footnote Common Stock 2021-09-07 5 G 0 877135 0.00 A 877135 I See footnote Common Stock 2021-09-07 5 G 0 29739 0.00 A 140739 D Common Stock 115000 I See footnote The shares are held in the name of George A. Scangos, as Trustee of the Scangos-Wilson Family Trust dated May 12, 2011. On August 30, 2018, the reporting person contributed 1,907,329 shares of the Issuer's common stock to the George A. Scangos 2018 Annuity Trust dated August 30, 2018 (the "Trust"), a grantor retained annuity trust for the benefit of himself and his children. Upon termination of the Trust, an aggregate of 1,877,590 of the shares were transferred to trusts for the benefit of each of his daughters, of which he and his spouse serve as trustees. The remaining 29,739 shares were distributed to the reporting person. The shares are held in the name of the Jennifer Scangos 2018 Exempt Trust, dated August 30, 2018, of which the reporting person and his spouse are Trustees. The shares are held in the name of the Jennifer Scangos 2018 Non-Exempt Trust, dated August 30, 2018, of which the reporting person and his spouse are Trustees. The shares are held in the name of the Katherine Scangos 2018 Exempt Trust, dated August 30, 2018, of which the reporting person and his spouse are Trustees. The shares are held in the name of the Katherine Scangos 2018 Non-Exempt Trust, dated August 30, 2018, of which the reporting person and his spouse are Trustees. The shares are held in the name of the Scangos 2018 Grandchildren's Trust, of which the reporting person and his spouse are Trustees. /s/ Howard Horn, Attorney-in-Fact 2022-02-14