X0306 4 2021-11-03 0 0001706431 Vir Biotechnology, Inc. VIR 0001787370 Pang Phillip C/O VIR BIOTECHNOLOGY, INC. 499 ILLINOIS STREET, SUITE 500 SAN FRANCISCO CA 94158 0 1 0 0 Chief Medical Officer Common Stock 2021-11-03 4 M 0 5000 5.175 A 105277 D Common Stock 2021-11-03 4 S 0 5000 36.4661 D 100277 D Stock Option (Right to Buy) 5.175 2021-11-03 4 M 0 5000 0.00 D 2029-03-10 Common Stock 5000 47129 D The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on February 19, 2021. The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $36.22 to $36.76 per share, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. 1/4 of the shares subject to the stock option vested and became exercisable on March 11, 2020, and the remaining shares will vest in 36 equal monthly installments thereafter. /s/ Howard Horn, Attorney-in-Fact 2021-11-04