X0306 4 2021-05-21 0 0001706431 Vir Biotechnology, Inc. VIR 0001207792 MORE ROBERT J C/O VIR BIOTECHNOLOGY, INC. 499 ILLINOIS STREET, SUITE 500 SAN FRANCISCO CA 94158 1 0 0 0 Common Stock 2021-05-21 4 A 0 3374 0.00 D 92709 D Common Stock 486111 I See footnote Stock Option (Right to Buy) 45.28 2021-05-21 4 A 0 6748 0.00 A 2022-05-21 2031-05-20 Common Stock 6748 6748 D The shares are held by Alta Partners NextGen Fund I, L.P. (APNG 1). The reporting person is a managing director of Alta Partners NextGen Fund I Management, LLC, which is the general partner of APNG 1. As such, the reporting person may be deemed to beneficially own the shares held by APNG 1. However, the reporting person disclaims beneficial ownership of such securities, except to the extent of his pecuniary interest therein, and this report shall not be deemed to be an admission that the reporting person is the beneficial owner of such securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise. /s/ Howard Horn, Attorney-in-Fact 2021-05-25