X0306 4 2020-04-14 0 0001706431 Vir Biotechnology, Inc. VIR 0001202102 SCANGOS GEORGE A C/O VIR BIOTECHNOLOGY, INC. 499 ILLINOIS STREET, SUITE 500 SAN FRANCISCO CA 94158 1 1 0 0 President and CEO Common Stock 2020-04-14 4 J 0 236806 29.56 D 1907329 I See footnote Common Stock 2020-04-14 4 J 0 236806 29.56 A 4713559 D This transaction represents a substitution of assets in which 236,806 shares of the Issuer's common stock were transferred to the reporting person from the George A. Scangos 2018 Annuity Trust dated August 30, 2018 (the "GRAT") in exchange for other assets. The reporting person was the beneficial owner of the shares while they were held by the GRAT and remains the beneficial owner of the shares following their withdrawal from the GRAT. The reporting person believes that the transfer was exempt under Rule 16a-13 under the Securities Exchange Act of 1934. Represents the average of the reported high and low per share prices for the Issuer's common stock on the date of the transaction. The shares are held in the name of the GRAT, of which the reporting person and his spouse are trustees. The total number of shares of common stock reported herein as directly owned includes 78,087 shares previously reported as indirectly owned through the GRAT and subsequently distributed to the reporting person in accordance with the terms of the GRAT. /s/ Howard Horn, Attorney-in-Fact 2020-04-16