Balance Sheet Components - Schedule of Accrued and Other Liabilities (Details) - USD ($) $ in Thousands	Dec. 31, 2022	Dec. 31, 2021
Balance Sheet Related Disclosures [Abstract]
Milestone payable	$ 0	$ 95,000
Net profit-sharing constrained	357,762
Accrued royalties	10,447	58,672
Research and development expenses	48,880	28,073
Payroll and related expenses	28,286	29,753
Accrued income taxes	15,228	6,217
Excess funds payable under grant agreements	7,652	1,825
Operating lease liabilities, current	4,137	3,927
Other professional and consulting expenses	3,987	2,791
Other accrued expenses	12,711	10,254
Total accrued and other liabilities	$ 489,090	$ 236,512