Consolidated Statements of Operations - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020
Revenues:
Total revenues	$ 1,615,797	$ 1,095,415	$ 76,368
Operating expenses:
Cost of revenue	146,319	65,865	0
Research and development	474,648	448,006	302,411
Selling, general and administrative	161,762	160,793	70,937
Total operating expenses	782,729	674,664	373,348
Income (loss) from operations	833,068	420,751	(296,980)
Other income (expense):
Change in fair value of equity investments	(111,140)	138,049	0
Interest income	28,092	439	2,836
Other expense, net	4,260	(9,437)	(4,467)
Total other income (expense)	(78,788)	129,051	(1,631)
Income (loss) before provision for income taxes	754,280	549,802	(298,611)
Provision for income taxes	(238,443)	(21,218)	(54)
Net income (loss)	$ 515,837	$ 528,584	$ (298,665)
Net income (loss) per share, basic	$ 3.89	$ 4.07	$ (2.51)
Net income (loss) per share, diluted	$ 3.83	$ 3.96	$ (2.51)
Weighted-average shares outstanding, basic	132,606,767	129,884,967	119,159,424
Weighted-average shares outstanding, diluted	134,810,908	133,437,126	119,159,424
Collaboration Revenue [Member]
Revenues:
Revenues from contract with customers	$ 1,505,469	$ 917,194	$ 0
Contract Revenue [Member]
Revenues:
Revenues from contract with customers	52,714	169,874	44,498
Grant Revenue [Member]
Revenues:
Revenues not from contract	35,325	8,347	9,123
License [Member]
Revenues:
Revenues from contract with customers	$ 22,289	$ 0	$ 22,747