Net Income (Loss) Per Share (Tables)

12 Months Ended

Dec. 31, 2022

Earnings Per Share [Abstract]

Schedule of Basic and Diluted Net Income (loss) Per Share

	Year ended December 31,
	2022		2021		2020
Net income (loss), basic and diluted	$	515,837	$	528,584	$	(298,665	)
Weighted-average shares outstanding, basic		132,606,767		129,884,967		119,159,424
Weighted-average effect of dilutive securities:
Options to purchase common stock		2,130,212		3,513,438		—
Restricted shares subject to future vesting		73,851		35,488		—
Shares to purchase under Employee Stock Purchase Plan		78		—		—
Contingently issuable shares		—		3,233		—
Weighted-average shares outstanding, diluted		134,810,908		133,437,126		119,159,424
Net income (loss) per share, basic	$	3.89	$	4.07	$	(2.51	)
Net income (loss) per share, diluted	$	3.83	$	3.96	$	(2.51	)

Schedule of Potentially Dilutive Securities Not Included in the Diluted Per Share Calculations

Potentially dilutive securities that were not included in the diluted per share calculations because they would be anti-dilutive were as follows:

	As of December 31,
	2022		2021		2020
Options issued and outstanding		8,853,734		5,764,308		9,798,282
Restricted shares subject to future vesting		2,646,748		1,088,304		89,261
Warrants to purchase common stock		—		—		—
Total		11,500,482		6,852,612		9,887,543