Grant Agreements - Additional Information (Details) - USD ($) $ / shares in Units, $ in Thousands		3 Months Ended		6 Months Ended
	Jan. 12, 2022	Jun. 30, 2022	Jun. 30, 2021	Jun. 30, 2022	Jun. 30, 2021	Dec. 31, 2021
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Accrued and other liabilities		$ 354,086		$ 354,086		$ 236,512
Grant Revenue
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Revenue from grants		2,058	$ 3,082	4,579	$ 4,453
Human Immunodeficiency Virus ('HIV') Grant | Maximum
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Grant awarded amount. maximum		55,700		55,700
Vaccinal Antibody Grant | Grant Revenue
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Revenue from grants		2,100	$ 3,100	4,600	$ 4,500
Vaccinal Antibody Grant | Bill And Melinda Gates Foundation
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Deferred revenue		$ 22,300		$ 22,300		6,900
Common Stock, Shares Purchased	881,365
Common Stock, Shares Purchased, Share Price	$ 45.38
Common Stock, Shares Purchased , Aggregate Purchase Price	$ 40,000
Common stock, shares issued, fair market value	28,500
Closing stock price		$ 37.65		$ 37.65
Underlying shares, Premium received	$ 11,300
Accrued and other liabilities		$ 3,000		$ 3,000		$ 1,800