Collaboration revenue (Tables)

6 Months Ended

Jun. 30, 2022

Revenue Recognition [Abstract]

Schedule of Collaboration revenue

During the three and six months ended June 30, 2022, the Company recorded profit-sharing amounts and profit-sharing amounts constrained as components of collaboration revenue in the unaudited condensed consolidated statements of operations, as follows:

	Three Months Ended June 30,					Six Months Ended June 30,
	2022			2021		2022			2021
	(in thousands)
Collaboration revenue, net
Profit-sharing amount	$	342,492		$	5,333	$	1,572,148		$	5,333
Profit-sharing amount constrained		(397,433	)		—		(397,433	)		—
Total collaboration revenue, net	$	(54,941	)	$	5,333	$	1,174,715		$	5,333