Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2022	Mar. 31, 2021
CASH FLOWS FROM OPERATING ACTIVITIES:
Net income (loss)	$ 518,621	$ (168,911)
Adjustments to reconcile net income (loss) to net cash used in operating activities:
Depreciation and amortization	1,419	1,269
Amortization of intangible assets	133	133
Amortization of premiums (accretion of discounts) on investments, net	1,073	409
Payment of contingent consideration in excess of acquisition date fair value	(93,803)
Noncash lease expense	2,111	1,484
Change in fair value of equity investments	95,039	0
Change in estimated fair value of contingent consideration	(3,931)	44,462
Stock-based compensation	25,304	15,471
Other	209	19
Changes in operating assets and liabilities:
Receivable from collaboration	(450,082)	0
Prepaid expenses and other current assets	(247)	943
Other assets	(227)	(63)
Accounts payable	3,829	(1,317)
Accrued liabilities and other long-term liabilities	433,556	(18,827)
Operating lease liabilities	(493)	4
Deferred revenue	17,578	35,395
Net cash provided by (used in) operating activities	550,089	(89,529)
CASH FLOWS FROM INVESTING ACTIVITIES:
Proceeds from sale of an equipment	12
Purchases of property and equipment	(15,841)	(667)
Purchases of investments	(89,563)	(5,000)
Maturities of investments		93,201
Net cash provided by (used in) investing activities	(105,392)	87,534
CASH FLOWS FROM FINANCING ACTIVITIES:
Proceeds from issuance of common stock in connection with a grant agreement	28,462
Proceeds from issuance of common stock in connection with a collaboration agreement		85,213
Payment of contingent consideration	(1,197)
Payment of principal on financing lease obligation	(64)	(62)
Proceeds from exercise of stock options	484	2,352
Net cash provided by financing activities	27,685	87,503
Net increase in cash, cash equivalents and restricted cash and cash equivalents	472,382	85,508
Cash, cash equivalents and restricted cash and cash equivalents at beginning of period	363,415	451,487
Cash, cash equivalents and restricted cash and cash equivalents at end of period	835,797	536,995
NONCASH INVESTING AND FINANCING ACTIVITIES:
Property and equipment purchases included in accounts payable and accrued liabilities	8,338	378
Operating lease liabilities obtained in exchange of right-of-use asset	3,222
RECONCILIATION OF CASH, CASH EQUIVALENTS AND RESTRICTED CASH TO THE CONDENSED CONSOLIDATED BALANCE SHEETS:
Cash and cash equivalents	812,355	521,396
Restricted cash and cash equivalents, current	14,402	8,601
Restricted cash and cash equivalents, noncurrent	9,040	6,998
Total cash, cash equivalents and restricted cash	$ 835,797	$ 536,995