Income Taxes - Additional Information (Details) - USD ($)	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019	Dec. 31, 2018
Income Taxes [Line Items]
Increase/decrease in valuation allowance		$ 74,100,000	$ 42,300,000
Release of valuation allowance	$ 114,200,000
Unrecognized tax benefit	7,422,000	4,877,000	2,725,000	$ 2,404,000
Unrecognized tax benefits, if recognized, would reduce effective tax rate	0
Interest and penalties expense related to uncertain tax positions	0	$ 0
Interest and penalties accrued related to uncertain tax positions			$ 0
Federal
Income Taxes [Line Items]
Net operating loss carryforwards	$ 24,200,000
Net operating loss carryforwards expiration beginning year	2035
Net operating loss deduction limitation as percentage of taxable income	80.00%
Tax credit carryforwards	$ 6,000,000.0
Federal | Research Tax Credit Carryforward
Income Taxes [Line Items]
Net operating loss carryforwards expiration beginning year	2036
State
Income Taxes [Line Items]
Net operating loss carryforwards	$ 126,600,000
Net operating loss carryforwards expiration beginning year	2031
Tax credit carryforwards	$ 11,000,000.0
State | Oregon | Research Tax Credit Carryforward
Income Taxes [Line Items]
Net operating loss carryforwards expiration beginning year	2022
Foreign | Swiss Federal Tax Administration (FTA)
Income Taxes [Line Items]
Net operating loss carryforwards	$ 0
Foreign | Australian Taxation Office
Income Taxes [Line Items]
Net operating loss carryforwards	$ 5,400,000