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Collaboration and License Agreements - Additional Information (Details)
1 Months Ended 3 Months Ended 6 Months Ended 12 Months Ended
Mar. 25, 2021
USD ($)
$ / shares
Feb. 14, 2021
USD ($)
Feb. 14, 2021
USD ($)
Program
Apr. 29, 2020
USD ($)
Unit
$ / shares
shares
Feb. 28, 2020
May 31, 2018
USD ($)
Oct. 31, 2017
USD ($)
shares
Jun. 30, 2020
USD ($)
Mar. 31, 2020
USD ($)
shares
Aug. 31, 2019
USD ($)
Sep. 30, 2018
USD ($)
Antibodies
Jul. 31, 2018
USD ($)
Product
May 31, 2018
USD ($)
Program
Oct. 31, 2017
USD ($)
shares
Jun. 30, 2021
USD ($)
Mar. 31, 2021
shares
Jun. 30, 2020
USD ($)
shares
Mar. 31, 2020
USD ($)
Jun. 30, 2020
USD ($)
Dec. 31, 2021
USD ($)
Dec. 31, 2020
USD ($)
Dec. 31, 2019
USD ($)
May 28, 2021
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                                              
Cost of revenue                                       $ 65,865,000 $ 0 $ 0  
Receivable from collaboration                                       773,079,000 0    
Contract Revenue                                              
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                                              
Total revenues                                       169,874,000 44,498,000 711,000  
License                                              
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                                              
Total revenues                                       0 22,747,000 0  
Collaboration Revenue [Member]                                              
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                                              
Total revenues                                       917,194,000 0 0  
2020 GSK | Collaboration Revenue [Member]                                              
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                                              
Total revenues                                       917,200      
GSK | Accrued Liabilities And Other Liabilities                                              
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                                              
Receivable from collaboration                                       773,100,000      
2021 GSK                                              
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                                              
Deferred revenue                                       $ 91,500,000      
2020 Stock Purchase Agreement | GGL                                              
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                                              
Issuance of common stock, shares | shares       6,626,027                                      
Share purchase price per share | $ / shares       $ 37.73                                      
Issuance of common stock       $ 250,000,000.0                                      
Preliminary Collaboration Agreement | 2020 GSK                                              
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                                              
Number of years conduct certain research and development activities under mutually agreed development plans       4 years                                      
Maximum percentage of right to perform details in connection with antibody product       20.00%                                      
Termination description                                       Either party has the right to terminate the 2020 GSK Agreement in the case of the insolvency of the other party, an uncured material breach of the other party with respect to a collaboration program or collaboration product, or as mutually agreed by the parties.      
Number of units of account | Unit       4                                      
Research and development expense                                       $ 77,300,000 25,400,000    
Collaboration type and program               The collaboration is focused on the development and commercialization of three types of collaboration products under three programs: (1) antibodies targeting SARS-CoV-2, and potentially other coronaviruses (the “Antibody Program”); (2) vaccines targeting SARS-CoV-2, and potentially other coronaviruses (the “Vaccine Program”), and (3) products based on genome-wide CRISPR screening of host targets expressed in connection with exposure to SARS-CoV-2, and potentially other coronaviruses (the “Functional Genomics Program”).                              
Preliminary Collaboration Agreement | 2020 GSK | Antibody Program                                              
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                                              
Percentage of development costs       72.50%                                      
Antibody license transaction price       $ 43,300,000                                      
Total revenues                                 $ 43,300,000            
Preliminary Collaboration Agreement | 2020 GSK | Vaccine Program                                              
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                                              
Percentage of development costs       27.50%                                      
Preliminary Collaboration Agreement | 2021 GSK                                              
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                                              
Number of separate programs | Program     3                                        
Upfront payment receivable   $ 225,000,000.0 $ 225,000,000.0                                        
Percentage of upfront payment receivable at effective date of agreement   50.00% 50.00%                                        
Option exercise fee to be received   $ 300,000,000.0 $ 300,000,000.0                                        
Preliminary Collaboration Agreement | 2021 GSK | Maximum                                              
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                                              
Pre-defined regulatory milestone payment   200,000,000.0 $ 200,000,000.0                                        
2020 Preliminary Collaboration Agreement and Stock Purchase Agreement | GGL | ASC 606                                              
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                                              
Fair market value of the common stock issued       $ 206,700,000                                      
Common stock price per share | $ / shares       $ 36.70                                      
Premium received on sale price of common stock       $ 43,300,000                                      
Definitive Collaboration Agreement | 2021 GSK                                              
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                                              
Percentage of upfront payment receivable at execution date of agreement                                             50.00%
2021 Stock Purchase Agreement | GGL                                              
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                                              
Issuance of common stock, shares | shares                               1,924,927              
Issuance of common stock   $ 120,000,000.0                                          
2021 Preliminary Collaboration Agreement and Stock Purchase Agreement | GGL | ASC 606                                              
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                                              
Fair market value of the common stock issued $ 85,200,000                                            
Common stock price per share | $ / shares $ 52.70                                            
Premium received on sale price of common stock $ 34,800,000                                            
2021 GSK Collaboration                                              
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                                              
Number of years conduct certain research and development activities under mutually agreed development plans   3 years                                          
Percentage of share development costs     50.00%                                        
Percentage of share Profit and loss     50.00%                                        
2021 GSK Agreement                                              
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                                              
Premium received on sale price of common stock     $ 34,800,000                                        
Research and development expense                                       500,000      
Upfront fee   $ 225,000,000.0                                          
Collaboration Agreement Transaction Price Consideration   $ 259,800,000                                          
2021 GSK Agreement | Contract Revenue                                              
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                                              
Total revenues                             $ 168,300,000                
Brii Agreement                                              
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                                              
Termination description           Each party may terminate for convenience all rights and obligations with respect to any program for which it has an option, with 30 days’ written notice (if the terminating party has not exercised an option for such program) or 180 days’ notice (following the exercise of an option for such program). The Brii Agreement may also be terminated by either party for insolvency of the other party, and either party may terminate the Brii Agreement in its entirety or on a program-by-program basis for the other party’s uncured material breach on 60 days’ written notice (or 30 days’ notice following failure to make payment).                                  
Written notice period to terminate licensed program for uncured material breach                         60 days                    
Written notice to terminate licensed program if exercise                         180 days                    
Written notice to terminate licensed program if not exercise                         30 days                    
Written notice period to terminate licensed program for failure to make payment                         30 days                    
Brii Agreement | Development Programs Exercised by Vir                                              
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                                              
Option exercise fee, low end of the range           low tens of millions                                  
Regulatory milestone payment on licensed product, low end of the range                         low tens of millions                    
Regulatory milestone payment on licensed product, high end of the range           $ 100,000,000.0             $ 100,000,000.0                    
Option exercise fee, high end of the range           50,000,000.0             50,000,000.0                    
Maximum Aggregate Sales Milestone Payments                         $ 175,000,000.0                    
Brii Agreement | Development Programs Exercised by Brii                                              
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                                              
Range of royalty payment to be received               high-teens to high-twenties                              
Regulatory milestone payment to be received               $ 30,000,000.0                              
Maximum sales milestone to pay               175,000,000.0                 175,000,000.0   $ 175,000,000.0        
Option exercise fee, low end of the range                         mid-single-digit millions                    
Regulatory milestone payment on licensed product, low end of the range                         mid-single-digit millions                    
Regulatory milestone payment on licensed product, high end of the range           30,000,000.0             $ 30,000,000.0                    
Range of royalty payment to be paid                         mid-teens to the high-twenties                    
Option exercise fee, high end of the range           $ 20,000,000.0             $ 20,000,000.0                    
Maximum Aggregate Sales Milestone Payments                         $ 175,000,000.0                    
Brii Agreement | Brii Bio Parent                                              
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                                              
Deferred revenue               2,700,000                 2,700,000   2,700,000        
Payment to collaborator resulting from program option exercise                                     $ 10,000,000.0        
Maximum number of development program granted from Vir to Brii | Program | Program                         4                    
Maximum number of development program granted from Brii to Vir | Program | Program                         4                    
Percentage of ordinary share equal to outstanding share                         9.90%                    
Carrying value of investment at cost                             $ 5,700,000                
Option exercise fee received               20,000,000.0                              
Determined transaction price               $ 22,700,000                              
Brii Agreement | Brii Bio Parent | License                                              
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                                              
Revenue from Related Parties                                       0 22,700,000    
Brii Agreement | Brii Bio Parent | Biological Materials                                              
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                                              
Total revenues                                       $ 400,000 0    
Brii Agreement | Brii Bio                                              
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                                              
Royalty payment obligation expiration period after first commercial sales           10 years                                  
Contract liability           $ 3,800,000             $ 3,800,000                    
Brii Agreement | Alnylam Pharmaceuticals Inc | Research and Development Expense                                              
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                                              
Payment to collaborator resulting from program option exercise                                 $ 10,000,000.0            
Alnylam Agreement | Alnylam Pharmaceuticals Inc                                              
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                                              
Issuance of common stock, shares | shares                 1,111,111               1,111,111            
Written notice period to terminate licensed program for uncured material breach                           60 days                  
Written Notice period to terminate licensed program if under challenge                           30 days                  
Royalty payment obligation expiration period after first commercial sales                                       10 years      
Value of shares transferred to collaborator             $ 800,000             $ 800,000                  
Upfront fee paid                           $ 10,000,000.0                  
Maximum shares to be issued | shares             1,111,111             1,111,111                  
Estimated fair value of the derivative liability                 $ 29,200,000                 $ 29,200,000          
Milestone payments paid                                 $ 15,000,000.0 $ 15,000,000.0          
Expenses incurred under agreement                                       $ 11,200,000 11,500,000 18,100,000  
Written notice period for termination of licensed program                           90 days                  
Written notice period to terminate licensed program for failure to make payment                           30 days                  
Alnylam Agreement | Alnylam Pharmaceuticals Inc | First siRNA Product HBV                                              
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                                              
Range of tiered royalties to pay on net sales of products             The Company may also be required to pay Alnylam tiered royalties at percentages ranging from the low double-digits to mid-teens on annual net sales of HBV products, and tiered royalties at percentages ranging from the high single-digits to the sub-teen double-digits on annual net sales of licensed infectious disease products, in each case subject to specified reductions and offsets.             low double-digits to mid-teens                  
Maximum milestone payment for achievement of specified development and regulatory                           $ 190,000,000.0                  
Maximum aggregate sales milestone payment                           $ 250,000,000.0                  
Alnylam Agreement | Alnylam Pharmaceuticals Inc | Each Infectious Disease siRNA                                              
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                                              
Range of tiered royalties to pay on net sales of products                           high single-digits to the sub-teen double-digits                  
Maximum milestone payment for achievement of specified development and regulatory                           $ 115,000,000.0                  
Maximum sales milestone payment                           $ 100,000,000.0                  
Development and Manufacturing Collaboration Agreement | WuXi Biologics                                              
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                                              
Termination description         the WuXi Biologics Collaboration Agreement may be terminated by (i) the written agreement of both parties, (ii) WuXi Biologics following the one year anniversary of the WuXi Biologics Collaboration Agreement effective date with respect to the entire agreement or on a product by product basis with 90 days’ prior written notice or (iii) by either party if the other party materially breaches the WuXi Biologics Collaboration Agreement and fails to cure such breach within 60 days.                                    
Royalties payment range on net sales of licensed product         high single-digits to mid-teens                                    
Rockefeller Agreement | Rockefeller                                              
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                                              
Termination description                       The Company has the right to terminate the Rockefeller Agreement in its entirety, or in part, for any reason on 60 days’ written notice to Rockefeller. Rockefeller may terminate the Rockefeller Agreement on 90 days’ written notice for the Company’s uncured material breach, or if the Company challenges the validity or enforceability of any of the licensed patents, or immediately in the event of the Company’s insolvency. Rockefeller may also terminate the Rockefeller Agreement if the Company ceases to carry on business with respect to the rights granted to the Company under the agreement.                      
Written notice period to terminate agreement by company                       60 days                      
Annual License Maintenance Fees                       $ 1,000,000.0                      
Written notice period to terminate agreement by counterparty                       90 days                      
Upfront fee paid                       $ 300,000                      
Royalty obligation period from date of first commercial sale                       12 years                      
Research and development expense under license agreement                                       4,700,000 1,300,000 1,000,000.0  
Rockefeller Agreement | Rockefeller | Infectious Disease Product                                              
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                                              
Maximum aggregate milestone payment for achievement of specified milestones                       $ 80,300,000                      
Rockefeller Agreement | Rockefeller | Infectious Disease Product [Member]                                              
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                                              
Maximum number of products covered against milestone payment | Product                       6                      
MedImmune Agreement | Influenza A and Influenza B                                              
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                                              
Royalties payment range on net sales of licensed product                     mid-single-digits to sub-teen double-digits                        
MedImmune Agreement | MedImmune                                              
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                                              
Number of antibodies to develop | Antibodies                     2                        
License agreement upfront payment                     $ 10,000,000.0                        
MedImmune Agreement | MedImmune | Influenza A and Influenza B                                              
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                                              
Termination description                     The Company may terminate the MedImmune Agreement in its entirety or on a product-by-product basis, for convenience, upon 120 days’ notice. Either party may terminate the MedImmune Agreement for cause for the other party’s uncured material breach on 60 days’ notice or immediately in the event of bankruptcy of the other party. Additionally, MedImmune may terminate the MedImmune Agreement for cause on 30 days’ written notice if the Company challenges the validity or enforceability of the patents to which the Company has obtained a license under the MedImmune Agreement.                        
Written notice period to terminate licensed program for uncured material breach                     60 days                        
Maximum aggregate milestone payment for achievement of specified milestones                     $ 331,500,000                        
Written notice period for termination of licensed program                     120 days                        
Written Notice period to terminate licensed program if under challenges                     30 days                        
2019 Xencor Agreement | Xencor | Research and Development Expense                                              
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                                              
Specified research and development expenses milestone payments                                       $ 500,000 $ 300,000 $ 800,000  
2019 Xencor Agreement | Xencor | HBV Program                                              
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                                              
Maximum aggregate milestone payments                   $ 77,800,000                          
2019 Xencor Agreement | Xencor | Influenza A Research Programs                                              
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                                              
Maximum aggregate milestone payments                   $ 77,800,000                          
2019 Xencor Agreement | Xencor | Influenza A and HBV Research Programs                                              
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                                              
Royalties payment range on net sales of licensed product                   low- to mid-single-digits                          
Maximum aggregate milestone payments                   $ 155,500,000                          
Maximum aggregate development and regulatory milestone payments                   17,800,000                          
Maximum aggregate commercial sales milestone payments                   $ 60,000,000.0                          
2020 Xencor Agreement | Xencor                                              
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                                              
Royalties payment expiration period                                       12 years      
Royalties based on net sales of licensed products                                       mid-single-digits      
Cost of revenue                                       $ 52,700,000      
2019 and 2020 Xencor Agreement member | Xencor                                              
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                                              
Termination description                                       The Company may terminate each agreement in its entirety, or on a target-by-target basis, for convenience upon 60 days’ written notice. Either party may terminate each agreement for the other party’s uncured material breach upon 60 days’ written notice (or 30 days in the case of non-payment) or in the event of bankruptcy of the other party immediately upon written notice. Xencor may terminate each agreement immediately upon written notice if the Company challenges, or upon 30 days’ written notice if any of the Company’s sublicensees challenge, the validity or enforceability of any patent licensed to the Company under each respective agreement.      
Written notice period for uncured material breach                                       60 days      
Written notice period for termination of licensed program                                       60 days      
Written Notice period to terminate licensed program if under challenges                                       30 days      
Written notice period to terminate licensed program for failure to make payment                                       30 days