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Fair Value Measurements - Summary of Changes in Estimated Fair Value of Financial Liabilities (Details) - Level 3 - Contingent Consideration Liability
$ in Thousands
12 Months Ended
Dec. 31, 2021
USD ($)
Fair Value Liabilities Measured On Recurring Basis Unobservable Input Reconciliation [Line Items]  
Balance at December 31, 2020 $ 35,974
Changes in fair value 91,848
Reclassification of derivative liability to accrued liabilities upon achievement of development milestone (95,000)
Payment of contingent consideration upon achievement of the TomegaVax milestone (10,000)
Balance at December 31, 2021 $ 22,822