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Unaudited Condensed Consolidated Statements of Operations - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2026
Sep. 30, 2025
Sep. 30, 2026
Sep. 30, 2025
Revenues        
Product revenue, net $ 107,648 $ 115,361 $ 308,955 $ 330,095
Collaboration revenue 560 734 5,175 2,464
Total revenues 108,208 116,095 314,130 332,559
Expenses        
Cost of product revenue (51,305) (46,764) (137,782) (128,219)
Cost of collaboration revenue 0 (119) (20) (531)
Research and development (49,810) (47,928) (177,167) (159,271)
Selling, general, and administrative (70,071) (70,106) (208,013) (204,566)
Loss from operations (62,978) (48,822) (208,852) (160,028)
Interest income 5,731 8,345 18,057 25,794
Interest expenses (1,577) (1,400) (4,801) (3,848)
Foreign currency gains 10,528 6,422 40,430 9,909
Other income (expense), net 288 (508) 5,735 3,045
Loss before income tax (48,008) (35,963) (149,431) (125,128)
Income tax benefit 1,872 0 1,454 0
Net loss $ (46,136) $ (35,963) $ (147,977) $ (125,128)
Loss per share - basic (in dollars per share) $ (0.04) $ (0.03) $ (0.13) $ (0.11)
Loss per share - diluted (in dollars per share) $ (0.04) $ (0.03) $ (0.13) $ (0.11)
Weighted-average shares used in calculating net loss per ordinary share - basic (in shares) 1,123,397,940 1,102,072,680 1,116,916,210 1,091,690,340
Weighted-average shares used in calculating net loss per ordinary share - diluted (in shares) 1,123,397,940 1,102,072,680 1,116,916,210 1,091,690,340