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Unaudited Condensed Consolidated Statements of Operations - USD ($)
3 Months Ended 6 Months Ended
Jun. 30, 2025
Jun. 30, 2024
Jun. 30, 2025
Jun. 30, 2024
Revenues        
Product revenue, net $ 109,085,000 $ 100,106,000 $ 214,735,000 $ 187,255,000
Collaboration revenue 892,000 398,000 1,729,000 398,000
Total revenues 109,977,000 100,504,000 216,464,000 187,653,000
Expenses        
Cost of product revenue (43,003,000) (35,148,000) (81,455,000) (68,767,000)
Cost of collaboration revenue (217,000) (85,000) (412,000) (85,000)
Research and development (50,614,000) (61,625,000) (111,343,000) (116,270,000)
Selling, general, and administrative (71,038,000) (79,710,000) (134,460,000) (148,904,000)
Loss from operations (54,895,000) (76,064,000) (111,206,000) (146,373,000)
Interest income 8,843,000 9,330,000 17,449,000 18,988,000
Interest expenses (1,262,000) (492,000) (2,449,000) (605,000)
Foreign currency gains (losses) 2,837,000 (4,108,000) 3,488,000 (6,176,000)
Other income (expense), net 3,750,000 (8,943,000) 3,553,000 418,000
Loss before income tax (40,727,000) (80,277,000) (89,165,000) (133,748,000)
Income tax expense 0 0 0 0
Net loss $ (40,727,000) $ (80,277,000) $ (89,165,000) $ (133,748,000)
Loss per share - basic (in dollars per share) $ (0.04) $ (0.08) $ (0.08) $ (0.14)
Loss per share - diluted (in dollars per share) $ (0.04) $ (0.08) $ (0.08) $ (0.14)
Weighted-average shares used in calculating net loss per ordinary share - basic (in shares) 1,091,933,150 975,937,790 1,086,413,130 974,541,780
Weighted-average shares used in calculating net loss per ordinary share - diluted (in shares) 1,091,933,150 975,937,790 1,086,413,130 974,541,780