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Pay vs Performance Disclosure
 12 Months Ended
Dec. 31, 2024
USD ($)
Dec. 31, 2023
USD ($)
Dec. 31, 2022
USD ($)
Dec. 31, 2021
USD ($)
Dec. 31, 2020
USD ($)
Pay vs Performance Disclosure          
Pay vs Performance Disclosure, Table
Value of Initial Fixed $100 Investment Based On:
Year (1)(2)Summary Compensation Table Total for CEO Compensation Actually Paid to CEO (3)Average Summary Compensation Table Total for Non-CEO
NEOs 		Average Compensation Actually Paid to Non-CEO
NEOs (3)		ZLAB TSR (4)
Peer Group TSR (4)
Net Income (Loss)
(in millions)
Revenue Growth (5)
$$$$$$$%
20249,079,948 1,724,268 3,622,883 4,795,966 62.97118.20(257.1)50 
202312,042,285 7,520,941 3,887,222 2,298,340 65.71118.87(334.6)24 
202220,212,141 739,598 6,838,043 3,550,025 73.82113.65(443.3)49 
202115,315,579 (30,500,547)6,176,702 (4,953,702)151.12126.45(704.5)195 
20208,536,036 112,741,937 3,401,688 22,814,071 325.41126.42(268.9)277 
        
Company Selected Measure Name Revenue growth        
Named Executive Officers, Footnote Samantha (Ying) Du is the CEO in each covered fiscal year.The non-CEO NEOs included the following executives in each covered fiscal year:
2024: Yajing Chen, Rafael Amado, F. Ty Edmondson, and Josh Smiley;
2023: Yajing Chen, Rafael Amado, Harald Reinhart, Josh Smiley, and Billy Cho;
2022: Billy Cho, Rafael Amado, Harald Reinhart, Alan Bart Sandler, and Josh Smiley;
2021: Billy Cho, F. Ty Edmondson, Harald Reinhart, and Alan Bart Sandler; and
2020: Billy Cho, F. Ty Edmondson, Alan Bart Sandler, and Tao Fu.
        
PEO Total Compensation Amount $ 9,079,948 $ 12,042,285 $ 20,212,141 $ 15,315,579 $ 8,536,036
PEO Actually Paid Compensation Amount $ 1,724,268 7,520,941 739,598 (30,500,547) 112,741,937
Adjustment To PEO Compensation, Footnote Deductions from, and additions to, total compensation in the Summary Compensation Table by year to calculate Compensation Actually Paid to our CEO and our Non-CEO NEOs are shown in the tables below. The amounts reflected for certain fiscal years have been revised from the amounts previously reported in last year’s proxy statement in order to incorporate administrative corrections in the calculation of fair value for certain stock and options awards.
CEO
2024
2023
2022
2021
2020
$
$
$
$
$
Summary Compensation Table Total
9,079,948 12,042,285 20,212,141 15,315,579 8,536,036 
Adjustments for Stock and Option Awards*
Adjustment for grant date fair values in the Summary Compensation Table
(7,319,338)(10,343,463)(18,545,040)(13,672,864)(7,160,000)
Year-end fair value of unvested awards granted in the covered fiscal year
2,592,810 7,756,321 13,913,094 3,708,060 27,099,276 
Year-over-year difference of year-end fair values for unvested awards granted in prior years that remained outstanding at the covered fiscal year end
(458,907)(2,184,985)(10,827,207)(36,638,677)66,533,031 
Fair values at vest date for awards granted and vested in covered fiscal year
— — — — — 
Difference in fair values between prior year-end fair values and vest date fair values for awards granted in prior years and vesting in the covered fiscal year
(2,170,245)250,783 (4,013,390)787,355 17,733,594 
Forfeitures during covered year equal to prior year-end fair value
— — — — — 
Incremental fair value resulting from modifications of stock options and RSUs in the covered fiscal year not reflected in the other rows
— — — — — 
Compensation Actually Paid (as calculated)
1,724,268 7,520,941 739,598 (30,500,547)112,741,937 
Average Non-CEO NEO
2024
2023
2022
2021
2020
$$$$$
Summary Compensation Table Total
3,622,883 3,887,222 6,838,043 6,176,702 3,401,688 
Adjustments for Stock and Option Awards*
Adjustment for grant date fair values in the Summary Compensation Table
(2,681,878)(2,879,951)(6,059,426)(5,279,647)(2,837,222)
Year-end fair value of unvested awards granted in the covered fiscal year
4,416,161 1,764,936 4,783,831 1,299,614 4,659,848 
Year-over-year difference of year-end fair values for unvested awards granted in prior years that remained outstanding at the covered fiscal year end
(119,636)(462,102)(1,408,060)(7,338,300)16,035,472 
Fair values at vest date for awards granted and vested in covered fiscal year
— — — 259,613 — 
Difference in fair values between prior year-end fair values and vest date fair values for awards granted in prior years and vesting in the covered fiscal year
(441,564)(42,600)(604,363)(71,684)1,554,285 
Forfeitures during covered fiscal year equal to prior year-end fair value
— (419,154)— — — 
Incremental fair value resulting from modifications of stock options and RSUs in the covered fiscal year not reflected in the other rows
— 449,989 — — — 
Compensation Actually Paid (as calculated)
4,795,966 2,298,340 3,550,025 (4,953,702)22,814,071 
*Adjustments are calculated using the same methodology as used in the Company’s financial statements under generally accepted accounting principles and, for awards subject to performance-based vesting conditions, based on the probable outcome of such performance-based vesting conditions as of the last day of the applicable fiscal year.
        
Non-PEO NEO Average Total Compensation Amount $ 3,622,883 3,887,222 6,838,043 6,176,702 3,401,688
Non-PEO NEO Average Compensation Actually Paid Amount $ 4,795,966 2,298,340 3,550,025 (4,953,702) 22,814,071
Adjustment to Non-PEO NEO Compensation Footnote Deductions from, and additions to, total compensation in the Summary Compensation Table by year to calculate Compensation Actually Paid to our CEO and our Non-CEO NEOs are shown in the tables below. The amounts reflected for certain fiscal years have been revised from the amounts previously reported in last year’s proxy statement in order to incorporate administrative corrections in the calculation of fair value for certain stock and options awards.
CEO
2024
2023
2022
2021
2020
$
$
$
$
$
Summary Compensation Table Total
9,079,948 12,042,285 20,212,141 15,315,579 8,536,036 
Adjustments for Stock and Option Awards*
Adjustment for grant date fair values in the Summary Compensation Table
(7,319,338)(10,343,463)(18,545,040)(13,672,864)(7,160,000)
Year-end fair value of unvested awards granted in the covered fiscal year
2,592,810 7,756,321 13,913,094 3,708,060 27,099,276 
Year-over-year difference of year-end fair values for unvested awards granted in prior years that remained outstanding at the covered fiscal year end
(458,907)(2,184,985)(10,827,207)(36,638,677)66,533,031 
Fair values at vest date for awards granted and vested in covered fiscal year
— — — — — 
Difference in fair values between prior year-end fair values and vest date fair values for awards granted in prior years and vesting in the covered fiscal year
(2,170,245)250,783 (4,013,390)787,355 17,733,594 
Forfeitures during covered year equal to prior year-end fair value
— — — — — 
Incremental fair value resulting from modifications of stock options and RSUs in the covered fiscal year not reflected in the other rows
— — — — — 
Compensation Actually Paid (as calculated)
1,724,268 7,520,941 739,598 (30,500,547)112,741,937 
Average Non-CEO NEO
2024
2023
2022
2021
2020
$$$$$
Summary Compensation Table Total
3,622,883 3,887,222 6,838,043 6,176,702 3,401,688 
Adjustments for Stock and Option Awards*
Adjustment for grant date fair values in the Summary Compensation Table
(2,681,878)(2,879,951)(6,059,426)(5,279,647)(2,837,222)
Year-end fair value of unvested awards granted in the covered fiscal year
4,416,161 1,764,936 4,783,831 1,299,614 4,659,848 
Year-over-year difference of year-end fair values for unvested awards granted in prior years that remained outstanding at the covered fiscal year end
(119,636)(462,102)(1,408,060)(7,338,300)16,035,472 
Fair values at vest date for awards granted and vested in covered fiscal year
— — — 259,613 — 
Difference in fair values between prior year-end fair values and vest date fair values for awards granted in prior years and vesting in the covered fiscal year
(441,564)(42,600)(604,363)(71,684)1,554,285 
Forfeitures during covered fiscal year equal to prior year-end fair value
— (419,154)— — — 
Incremental fair value resulting from modifications of stock options and RSUs in the covered fiscal year not reflected in the other rows
— 449,989 — — — 
Compensation Actually Paid (as calculated)
4,795,966 2,298,340 3,550,025 (4,953,702)22,814,071 
*Adjustments are calculated using the same methodology as used in the Company’s financial statements under generally accepted accounting principles and, for awards subject to performance-based vesting conditions, based on the probable outcome of such performance-based vesting conditions as of the last day of the applicable fiscal year.
        
Compensation Actually Paid vs. Total Shareholder Return
The illustrations below provide a graphical description of CAP (as calculated in accordance with the SEC rules) compared to: (1) our cumulative TSR and the cumulative TSR of the Peer Group, (2) our net income, and (3) revenue growth. Since a significant portion of compensation for our CEO and other named executive officers consists of equity awards, the change in value of Compensation Actually Paid is directionally aligned with changes in our TSR, net income, and revenue growth.
CAP Versus Cumulative TSR for the Company and Cumulative TSR of the Peer Group
Picture1_4.11.jpg
        
Compensation Actually Paid vs. Net Income
The illustrations below provide a graphical description of CAP (as calculated in accordance with the SEC rules) compared to: (1) our cumulative TSR and the cumulative TSR of the Peer Group, (2) our net income, and (3) revenue growth. Since a significant portion of compensation for our CEO and other named executive officers consists of equity awards, the change in value of Compensation Actually Paid is directionally aligned with changes in our TSR, net income, and revenue growth.
CAP Versus Net Income
Picture2_4.11.jpg
        
Compensation Actually Paid vs. Company Selected Measure
The illustrations below provide a graphical description of CAP (as calculated in accordance with the SEC rules) compared to: (1) our cumulative TSR and the cumulative TSR of the Peer Group, (2) our net income, and (3) revenue growth. Since a significant portion of compensation for our CEO and other named executive officers consists of equity awards, the change in value of Compensation Actually Paid is directionally aligned with changes in our TSR, net income, and revenue growth.
CAP Versus Revenue Growth
Picture3_4.11.jpg
        
Total Shareholder Return Vs Peer Group
The illustrations below provide a graphical description of CAP (as calculated in accordance with the SEC rules) compared to: (1) our cumulative TSR and the cumulative TSR of the Peer Group, (2) our net income, and (3) revenue growth. Since a significant portion of compensation for our CEO and other named executive officers consists of equity awards, the change in value of Compensation Actually Paid is directionally aligned with changes in our TSR, net income, and revenue growth.
CAP Versus Cumulative TSR for the Company and Cumulative TSR of the Peer Group
Picture1_4.11.jpg
        
Tabular List, Table Revenue growth
•Product revenues
•Commercial profitability
•Year-end cash and cash equivalents
        
Total Shareholder Return Amount $ 62.97 65.71 73.82 151.12 325.41
Peer Group Total Shareholder Return Amount 118.2 118.87 113.65 126.45 126.42
Net Income (Loss) $ (257,100,000) $ (334,600,000) $ (443,300,000) $ (704,500,000) $ (268,900,000)
Company Selected Measure Amount 0.50 0.24 0.49 1.95 2.77
PEO Name Samantha (Ying) Du        
Additional 402(v) Disclosure TSR is determined based on the value of an initial fixed investment of $100, and the reinvestment of all dividends are assumed. The peer group consists of the NASDAQ Biotechnology Index.        
Measure:: 1          
Pay vs Performance Disclosure          
Name Revenue growth        
Non-GAAP Measure Description Revenue growth is calculated as follows: (total revenues from our audited annual consolidated statements of operations for the current year - total revenues from our audited annual consolidated statements of operations for the prior year) / total revenues from our audited annual consolidated statements of operations for the prior year.        
Measure:: 2          
Pay vs Performance Disclosure          
Name Product revenues        
Measure:: 3          
Pay vs Performance Disclosure          
Name Commercial profitability        
Measure:: 4          
Pay vs Performance Disclosure          
Name Year-end cash and cash equivalents        
PEO | Aggregate Grant Date Fair Value of Equity Award Amounts Reported in Summary Compensation Table          
Pay vs Performance Disclosure          
Adjustment to Compensation, Amount $ (7,319,338) $ (10,343,463) $ (18,545,040) $ (13,672,864) $ (7,160,000)
PEO | Year-end Fair Value of Equity Awards Granted in Covered Year that are Outstanding and Unvested          
Pay vs Performance Disclosure          
Adjustment to Compensation, Amount 2,592,810 7,756,321 13,913,094 3,708,060 27,099,276
PEO | Year-over-Year Change in Fair Value of Equity Awards Granted in Prior Years That are Outstanding and Unvested          
Pay vs Performance Disclosure          
Adjustment to Compensation, Amount (458,907) (2,184,985) (10,827,207) (36,638,677) 66,533,031
PEO | Vesting Date Fair Value of Equity Awards Granted and Vested in Covered Year          
Pay vs Performance Disclosure          
Adjustment to Compensation, Amount 0 0 0 0 0
PEO | Change in Fair Value as of Vesting Date of Prior Year Equity Awards Vested in Covered Year          
Pay vs Performance Disclosure          
Adjustment to Compensation, Amount (2,170,245) 250,783 (4,013,390) 787,355 17,733,594
PEO | Prior Year End Fair Value of Equity Awards Granted in Any Prior Year that Fail to Meet Applicable Vesting Conditions During Covered Year          
Pay vs Performance Disclosure          
Adjustment to Compensation, Amount 0 0 0 0 0
PEO | Dividends or Other Earnings Paid on Equity Awards not Otherwise Reflected in Total Compensation for Covered Year          
Pay vs Performance Disclosure          
Adjustment to Compensation, Amount 0 0 0 0 0
Non-PEO NEO | Aggregate Grant Date Fair Value of Equity Award Amounts Reported in Summary Compensation Table          
Pay vs Performance Disclosure          
Adjustment to Compensation, Amount (2,681,878) (2,879,951) (6,059,426) (5,279,647) (2,837,222)
Non-PEO NEO | Year-end Fair Value of Equity Awards Granted in Covered Year that are Outstanding and Unvested          
Pay vs Performance Disclosure          
Adjustment to Compensation, Amount 4,416,161 1,764,936 4,783,831 1,299,614 4,659,848
Non-PEO NEO | Year-over-Year Change in Fair Value of Equity Awards Granted in Prior Years That are Outstanding and Unvested          
Pay vs Performance Disclosure          
Adjustment to Compensation, Amount (119,636) (462,102) (1,408,060) (7,338,300) 16,035,472
Non-PEO NEO | Vesting Date Fair Value of Equity Awards Granted and Vested in Covered Year          
Pay vs Performance Disclosure          
Adjustment to Compensation, Amount 0 0 0 259,613 0
Non-PEO NEO | Change in Fair Value as of Vesting Date of Prior Year Equity Awards Vested in Covered Year          
Pay vs Performance Disclosure          
Adjustment to Compensation, Amount (441,564) (42,600) (604,363) (71,684) 1,554,285
Non-PEO NEO | Prior Year End Fair Value of Equity Awards Granted in Any Prior Year that Fail to Meet Applicable Vesting Conditions During Covered Year          
Pay vs Performance Disclosure          
Adjustment to Compensation, Amount 0 (419,154) 0 0 0
Non-PEO NEO | Dividends or Other Earnings Paid on Equity Awards not Otherwise Reflected in Total Compensation for Covered Year          
Pay vs Performance Disclosure          
Adjustment to Compensation, Amount $ 0 $ 449,989 $ 0 $ 0 $ 0