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Consolidated Statements of Shareholders' Equity - USD ($)
$ in Thousands
Total
Ordinary shares
Additional paid in capital
Accumulated deficit
Accumulated other comprehensive income (loss)
Treasury Stock
Beginning balance (in shares) at Dec. 31, 2021   955,363,980        
Beginning balance at Dec. 31, 2021 $ 1,379,956 $ 6 $ 2,825,948 $ (1,418,074) $ (23,645) $ (4,279)
Beginning balance (in shares) at Dec. 31, 2021           (382,930)
Increase (Decrease) in Stockholders' Equity [Roll Forward]            
Issuance of ordinary shares upon vesting of restricted shares (in shares)   1,940,680        
Issuance of ordinary shares upon vesting of restricted shares 0 $ 0 0      
Exercise of shares options (in shares)   5,151,190        
Exercise of share options 5,870 $ 0 5,870      
Receipt of shares netted to satisfy tax withholding obligations related to share-based compensation (in shares)           (1,853,350)
Receipt of shares netted to satisfy tax withholding obligations related to share-based compensation (7,577)         $ (7,577)
Share-based compensation 61,302   61,302      
Net loss (443,286)     (443,286)    
Foreign currency translation 49,330       49,330  
Ending balance (in shares) at Dec. 31, 2022   962,455,850        
Ending balance at Dec. 31, 2022 1,045,595 $ 6 2,893,120 (1,861,360) 25,685 $ (11,856)
Ending balance (in shares) at Dec. 31, 2022           (2,236,280)
Increase (Decrease) in Stockholders' Equity [Roll Forward]            
Issuance of ordinary shares upon vesting of restricted shares (in shares)   8,178,500        
Issuance of ordinary shares upon vesting of restricted shares 0 $ 0 0      
Exercise of shares options (in shares)   6,516,920        
Exercise of share options 2,548 $ 0 2,548      
Receipt of shares netted to satisfy tax withholding obligations related to share-based compensation (in shares)           (2,675,920)
Receipt of shares netted to satisfy tax withholding obligations related to share-based compensation (8,980)         $ (8,980)
Share-based compensation 79,634   79,634      
Net loss (334,620)     (334,620)    
Foreign currency translation $ 11,941       11,941  
Ending balance (in shares) at Dec. 31, 2023 972,239,070 977,151,270        
Ending balance at Dec. 31, 2023 $ 796,118 $ 6 2,975,302 (2,195,980) 37,626 $ (20,836)
Ending balance (in shares) at Dec. 31, 2023 (4,912,200)         (4,912,200)
Increase (Decrease) in Stockholders' Equity [Roll Forward]            
Issuance of ordinary shares upon vesting of restricted shares (in shares)   10,120,260        
Issuance of ordinary shares upon vesting of restricted shares $ 0 $ 0 0      
Exercise of shares options (in shares) 5,147,140 5,147,140        
Exercise of share options $ 3,269 $ 0 3,269      
Issuance of ordinary shares upon follow-on public offering, net of issuance cost (in shares)   90,196,070        
Issuance of ordinary shares upon follow-on public offering, net of issuance cost 215,074 $ 1 215,073      
Share-based compensation 70,651   70,651      
Net loss (257,103)     (257,103)    
Foreign currency translation $ 12,889       12,889  
Ending balance (in shares) at Dec. 31, 2024 1,077,702,540 1,082,614,740        
Ending balance at Dec. 31, 2024 $ 840,898 $ 7 $ 3,264,295 $ (2,453,083) $ 50,515 $ (20,836)
Ending balance (in shares) at Dec. 31, 2024 (4,912,200)         (4,912,200)