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Insider Trading Arrangements
 3 Months Ended 12 Months Ended
Dec. 31, 2024
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Dec. 31, 2024
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Trading Arrangements, by Individual    
Material Terms of Trading Arrangement  
On November 20, 2024, Dr. Samantha (Ying) Du, the Company’s Founder, Chief Executive officer, and Chairperson of the Board, adopted a new written Rule 10b5-1 trading arrangement, for (1) the acquisition and sale of up to 589,165 ADSs upon the exercise of previously awarded options that are scheduled to expire in 2025 and (2) for the acquisition of up to 604,376 ADSs upon the exercise of previously awarded options that are scheduled to expire in 2025. This Rule 10b5-1 trading arrangement is scheduled to terminate no later than November 20, 2025.
On November 20, 2024, William Lis, one of the Company’s directors, adopted a new written Rule 10b5-1 trading arrangement for the sale of up to 26,690 ADSs. This Rule 10b5-1 trading arrangement is scheduled to terminate no later than June 1, 2026.
On November 22, 2024, Rafael Amado, the Company’s President and Head of Global Research and Development, adopted a new written Rule 10b5-1 trading arrangement for the sale of up to 9,000 ADSs. This Rule 10b5-1 trading arrangement is scheduled to terminate no later than December 17, 2025.
On November 22, 2024, F. Ty Edmondson, the Company’s Chief Legal Officer, adopted a new written Rule 10b5-1 trading arrangement for the sale of up to 28,872 ADSs. This Rule 10b5-1 trading arrangement is scheduled to terminate no later than November 21, 2025.
Non-Rule 10b5-1 Arrangement Adopted false  
Rule 10b5-1 Arrangement Terminated false  
Non-Rule 10b5-1 Arrangement Terminated false  
Expiration Date November 21, 2025  
Dr. Samantha (Ying) Du [Member]    
Trading Arrangements, by Individual    
Name Dr. Samantha (Ying) Du  
Title Founder, Chief Executive officer, and Chairperson of the Board  
Rule 10b5-1 Arrangement Adopted true  
Adoption Date November 20, 2024  
Expiration Date November 20, 2025  
Arrangement Duration 365 days  
William Lis [Member]    
Trading Arrangements, by Individual    
Name William Lis  
Title director  
Rule 10b5-1 Arrangement Adopted true  
Adoption Date November 20, 2024  
Expiration Date June 1, 2026  
Arrangement Duration 558 days  
Aggregate Available 26,690 26,690
Rafael Amado [Member]    
Trading Arrangements, by Individual    
Name Rafael Amado  
Title President and Head of Global Research and Development  
Rule 10b5-1 Arrangement Adopted true  
Adoption Date November 22, 2024  
Expiration Date December 17, 2025  
Arrangement Duration 390 days  
Aggregate Available 9,000 9,000
F. Ty Edmondson [Member]    
Trading Arrangements, by Individual    
Name F. Ty Edmondson  
Title Chief Legal Officer  
Rule 10b5-1 Arrangement Adopted true  
Adoption Date November 22, 2024  
Arrangement Duration 364 days  
Aggregate Available 28,872 28,872
Dr. Du Trading Arrangement, Options One [Member] | Dr. Samantha (Ying) Du [Member]    
Trading Arrangements, by Individual    
Aggregate Available 589,165 589,165
Dr. Du Trading Arrangement, Options Two [Member] | Dr. Samantha (Ying) Du [Member]    
Trading Arrangements, by Individual    
Aggregate Available 604,376 604,376