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Schedule I — Condensed Financial Information of Registrant - Condensed Statements of Operations and Comprehensive Loss (Details) - USD ($)
12 Months Ended
Dec. 31, 2023
Dec. 31, 2022
Dec. 31, 2021
Operating Expenses:      
Research and development $ (265,868,000) $ (286,408,000) $ (573,306,000)
Loss from operations (366,573,000) (404,357,000) (700,064,000)
Interest income 39,797,000 14,582,000 2,190,000
Other income (expense), net 7,006,000 3,113,000 (10,201,000)
Loss before income tax and share of loss from equity method investment (334,620,000) (443,065,000) (703,414,000)
Income tax expense 0 0 0
Net loss (334,620,000) (443,286,000) (704,471,000)
Other comprehensive income (loss) , net of tax of nil:      
Other comprehensive (loss) income, tax 0 0 0
Foreign currency translation adjustments 11,941,000 49,330,000 (9,121,000)
Comprehensive loss (322,679,000) (393,956,000) (713,592,000)
Parent Company      
Operating Expenses:      
Research and development (82,000) (178,000) (6,000)
General and administrative (16,958,000) (19,773,000) (12,074,000)
Loss from operations (17,040,000) (19,951,000) (12,080,000)
Interest income 30,840,000 12,857,000 1,881,000
Other income (expense), net 4,029,000 (8,678,000) (18,173,000)
Loss before income tax and share of loss from equity method investment 17,829,000 (15,772,000) (28,372,000)
Equity in loss of subsidiaries (352,449,000) (427,514,000) (676,099,000)
Income tax expense 0 0 0
Net loss (334,620,000) (443,286,000) (704,471,000)
Other comprehensive income (loss) , net of tax of nil:      
Other comprehensive (loss) income, tax 0 0 0
Foreign currency translation adjustments 11,941,000 49,330,000 (9,121,000)
Comprehensive loss $ (322,679,000) $ (393,956,000) $ (713,592,000)