Summary of Significant Accounting Policies - Additional Information (Details) $ / shares in Units, ¥ in Millions			1 Months Ended			12 Months Ended
	Mar. 30, 2022 USD ($) $ / shares shares	Mar. 29, 2022	Feb. 28, 2022 CNY (¥)	Apr. 30, 2020 CNY (¥)	Mar. 31, 2020 CNY (¥)	Dec. 31, 2022 USD ($) segment $ / shares shares	Dec. 31, 2021 USD ($) $ / shares shares	Dec. 31, 2020 USD ($)	Dec. 31, 2019	Dec. 31, 2022 CNY (¥) shares	Dec. 31, 2021 CNY (¥) shares
Significant Accounting Policies [Line Items]
Share Subdivision ratio	10
Ordinary shares, authorized share capital	$ 30,000
Ordinary shares, shares authorized (in shares) | shares	5,000,000,000					5,000,000,000	5,000,000,000			5,000,000,000	5,000,000,000
Ordinary shares, par value (in dollars per share) | $ / shares	$ 0.000006					$ 0.000006	$ 0.000006
ADS to ordinary shares conversion ratio	10	1
Allowance for credit loss						$ 0	$ 0
Land use rights lease term									30 years
Amortization expenses						500,000	500,000	$ 300,000
Finite-lived intangible assets, Amortization expense, year one						600,000
Finite-lived intangible assets, Amortization expense, year two						500,000
Finite-lived intangible assets, Amortization expense, year three						300,000
Finite-lived intangible assets, Amortization expense, year four						100,000
Finite-lived intangible assets, Amortization expense, year five						0
Finite-lived intangible assets, Amortization expense, after year five						0
Government grants recognized						11,471,000	4,113,000	7,289,000
Deferred income						$ 21,360,000	27,486,000
Reimbursement recognized period						5 years
Reimbursements recognized						$ 200,000	300,000	300,000
Collaboration revenue						2,368,000	207,000	0
Unrecognized tax benefits and related interest and penalties						$ 0
Number of operating segments | segment						1
Number of reportable segments | segment						1
Aggregate amount of cash and cash equivalents						$ 1,008,470,000	964,100,000	$ 442,116,000
Government Grants
Significant Accounting Policies [Line Items]
Deferred income						900,000	2,400,000
ADR program Reimbursements
Significant Accounting Policies [Line Items]
Deferred income						$ 0	$ 200,000
Foreign Currency Risk | Cash and Cash Equivalents
Significant Accounting Policies [Line Items]
Aggregate amount of cash and cash equivalents | ¥										¥ 316.8	¥ 151.7
China | Foreign Currency Risk | Cash and Cash Equivalents
Significant Accounting Policies [Line Items]
Concentration risk percentage						5.00%	2.00%
Level 1
Significant Accounting Policies [Line Items]
Equity investments with readily determinable fair value						$ 6,400,000	$ 15,400,000
Hanhui
Significant Accounting Policies [Line Items]
Upfront payment | ¥			¥ 70.0	¥ 90.0	¥ 230.0
Hanhui | Collaborative Agreement
Significant Accounting Policies [Line Items]
Deferred income						$ 20,500,000	$ 24,900,000
Amortization period for deferred income						10 years
Minimum
Significant Accounting Policies [Line Items]
Intangible assets amortization period						3 years
Maximum
Significant Accounting Policies [Line Items]
Intangible assets amortization period						5 years