Revenue

12 Months Ended

Dec. 31, 2022

Revenue from Contract with Customer [Abstract]

Revenue

Revenue

Product Revenue, Net

The Company’s product revenue is primarily derived from the sales of ZEJULA, Optune, QINLOCK, and NUZYRA in mainland China and Hong Kong. The table below presents the Company’s net product sales (in thousands):

	Year Ended December 31,
	2022	2021	2020
	$	$	$
Product revenue — gross	234,009	190,180	57,355
Less: Rebates and sales returns	(21,337)	(46,075)	(8,397)
Product revenue — net	212,672	144,105	48,958

Sales rebates are offered to distributors in mainland China, and the amounts are recorded as a reduction of revenue. Estimated rebates are determined based on contracted rates, sales volumes, and level of distributor inventories.

The following table presents net revenue by product (in thousands):

	Year Ended December 31,
	2022	2021	2020
	$	$	$
ZEJULA	145,194	93,579	32,138
Optune	47,321	38,903	16,418
QINLOCK	14,957	11,620	402
NUZYRA	5,200	3	—
Total product revenue — net	212,672	144,105	48,958

Collaboration Revenue

The Company’s collaboration revenue was $2.4 million, $0.2 million, and nil for 2022, 2021, and 2020, respectively. Accounts receivable arising from the Company’s collaborative arrangement were nil and $11.0 million as of December 31, 2022 and 2021, respectively. The collaboration revenue was from the Company’s exclusive promotion arrangement with Huizheng.