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Revenue
12 Months Ended
Dec. 31, 2022
Revenue from Contract with Customer [Abstract]  
Revenue Revenue
Product Revenue, Net
The Company’s product revenue is primarily derived from the sales of ZEJULA, Optune, QINLOCK, and NUZYRA in mainland China and Hong Kong. The table below presents the Company’s net product sales (in thousands):
Year Ended December 31,
202220212020
$
$
$
Product revenue — gross234,009 190,180 57,355 
Less: Rebates and sales returns(21,337)(46,075)(8,397)
Product revenue — net212,672 144,105 48,958 
Sales rebates are offered to distributors in mainland China, and the amounts are recorded as a reduction of revenue. Estimated rebates are determined based on contracted rates, sales volumes, and level of distributor inventories.
The following table presents net revenue by product (in thousands):
Year Ended December 31,
202220212020
$$$
ZEJULA145,194 93,579 32,138 
Optune47,321 38,903 16,418 
QINLOCK14,957 11,620 402 
NUZYRA5,200 — 
Total product revenue — net212,672 144,105 48,958 

Collaboration Revenue
The Company’s collaboration revenue was $2.4 million, $0.2 million, and nil for 2022, 2021, and 2020, respectively. Accounts receivable arising from the Company’s collaborative arrangement were nil and $11.0 million as of December 31, 2022 and 2021, respectively. The collaboration revenue was from the Company’s exclusive promotion arrangement with Huizheng.