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Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2019
Dec. 31, 2018
Dec. 31, 2017
Operating activities      
Net loss $ (195,071) $ (139,075) $ (50,384)
Adjustments to reconcile net loss to net cash used in operating activities:      
Depreciation and amortization expenses 3,766 1,650 548
Amortization of deferred income (312) (312) (78)
Share-based compensation 20,291 12,229 9,931
Share of loss from equity method investment 752 587 250
Loss on disposal of property and equipment 15 1 13
Noncash lease expenses 2,831    
Change in fair value of warrants     (200)
Changes in operating assets and liabilities:      
Accounts receivable (3,701) (90)  
Inventories (6,001) (4)  
Prepayments and other current assets (1,125) (4,794) (811)
Long term deposits 180 (250) (39)
Value added tax recoverable (5,693) (2,982) (3,685)
Accounts payable (14,772) 28,464 8,444
Other current liabilities 9,136 7,056 1,950
Operating lease liabilities (2,436)    
Deferred income 1,129 (18) 1,694
Net cash used in operating activities (191,011) (97,538) (32,367)
Cash flows from investing activities:      
Purchases of short-term investments (277,640) (200,350)  
Proceeds from maturity of short-term investments 277,990    
Disposal of long-term investment     500
Purchase of equity method investment   (2,086) (1,900)
Purchase of property and equipment (6,035) (10,015) (9,102)
Disposal of property and equipment     83
Purchase of land use rights (7,836)    
Purchase of intangible assets (1,371) (103) (15)
Net cash used in investing activities (14,892) (212,554) (10,434)
Cash flows from financing activities:      
Proceed from short-term borrowings 7,252 3,643  
Repayment of short-term borrowings (4,351)    
Proceed from issuance of convertible preferred shares, net of issuance cost     29,100
Proceeds from exercise of warrants     1,000
Proceeds from exercises of stock options 1,055 196 65
Proceeds from issuance of ordinary shares upon public offerings 216,200 141,000 160,425
Payment of public offering costs (854) (692) (2,730)
Net cash provided by financing activities 219,302 144,147 187,860
Effect of foreign exchange rate changes on cash, cash equivalents and restricted cash 91 (763) 652
Net increase (decrease) in cash, cash equivalents and restricted cash 13,490 (166,708) 145,711
Cash, cash equivalents and restricted cash - beginning of the year 62,952 229,660 83,949
Cash, cash equivalents and restricted cash - end of the year 76,442 62,952 229,660
Supplemental disclosure on non-cash investing and financing activities:      
Payables for purchase of property and equipment 416 1,709 414
Payables for intangible assets   225  
Payables for public offering costs     40
Conversion of convertible preferred shares     163,607
Exercise of warrants     3,700
Supplemental disclosure of cash flow information:      
Cash and cash equivalents 75,932 62,952 $ 229,660
Restricted cash, non-current 510    
Interest paid $ 288 $ 36