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Consolidated Statements of Operations - USD ($)
12 Months Ended
Dec. 31, 2018
Dec. 31, 2017
Dec. 31, 2016
Income Statement [Abstract]      
Revenue $ 129,452    
Cost of sales (43,590)    
Gross profit 85,862    
Operating expenses:      
Research and development (120,278,023) $ (39,341,518) $ (32,149,157)
Selling, general and administrative (21,575,921) (12,049,518) (6,380,144)
Loss from operations (141,768,082) (51,391,036) (38,529,301)
Interest income 3,260,634 527,351 403,266
Interest expense (39,672)    
Changes in fair value of warrants   200,000 (1,920,000)
Other income 1,968,325 933,158 2,533,966
Other expense (1,909,549) (403,997) (143)
Loss before income tax and share of loss from equity method investment (138,488,344) (50,134,524) (37,512,212)
Income tax expense 0    
Share of loss from equity method investment (586,551) (249,652)  
Net loss (139,074,895) (50,384,176) (37,512,212)
Net loss attributable to ordinary shareholders $ (139,074,895) $ (50,384,176) $ (37,512,212)
Loss per share - basic and diluted $ (2.64) $ (2.32) $ (3.97)
Weighted-average shares used in calculating net loss per ordinary share - basic and diluted 52,609,810 21,752,757 9,439,028