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Related party transactions - Additional Information (Details) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2021
Sep. 30, 2020
Sep. 30, 2021
Sep. 30, 2020
Research and development | MEDx (Suzhou) Translational Medicine Co., Ltd.        
Related Party Transaction [Line Items]        
Transactions between its related party $ 96 $ 233 $ 303 $ 417