Consolidated statements of operations - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2021	Sep. 30, 2020	Sep. 30, 2021	Sep. 30, 2020
Income Statement [Abstract]
Revenue	$ 43,103	$ 14,651	$ 100,141	$ 33,864
Expenses:
Cost of sales	(12,162)	(4,934)	(30,535)	(9,914)
Research and development	(55,144)	(58,100)	(401,220)	(160,149)
Selling, general and administrative	(59,002)	(27,874)	(149,254)	(70,346)
Loss from operations	(83,205)	(76,257)	(480,868)	(206,545)
Interest income	713	866	1,171	3,748
Interest expenses		(43)		(157)
Other (expenses) income, net	(13,580)	11,958	(12,401)	11,267
Loss before income tax and share of loss from equity method investment	(96,072)	(63,476)	(492,098)	(191,687)
Income tax expense
Share of loss from equity method investment	(340)	(265)	(548)	(671)
Net loss	(96,412)	(63,741)	(492,646)	(192,358)
Net loss attributable to ordinary shareholders	$ (96,412)	$ (63,741)	$ (492,646)	$ (192,358)
Loss per share - basic and diluted	$ (1.01)	$ (0.84)	$ (5.34)	$ (2.59)
Weighted-average shares used in calculating net loss per ordinary share - basic and diluted	95,035,432	75,436,646	92,174,838	74,381,115