<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0607</schemaVersion>

    <documentType>3/A</documentType>

    <periodOfReport>2026-03-18</periodOfReport>

    <dateOfOriginalSubmission>2026-03-18</dateOfOriginalSubmission>

    <noSecuritiesOwned>0</noSecuritiesOwned>

    <issuer>
        <issuerCik>0001075880</issuerCik>
        <issuerName>KAZIA THERAPEUTICS LTD</issuerName>
        <issuerTradingSymbol>KZIA</issuerTradingSymbol>
        <issuerForeignTradingSymbol></issuerForeignTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001704021</rptOwnerCik>
            <rptOwnerName>Friend John E. II</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerNonUSAddressFlag>true</rptOwnerNonUSAddressFlag>
            <rptOwnerStreet1>THREE INTERNATIONAL TOWERS</rptOwnerStreet1>
            <rptOwnerStreet2>LEVEL 24, 300 BARANGAROO AVE</rptOwnerStreet2>
            <rptOwnerCity>SYDNEY, NSW</rptOwnerCity>
            <rptOwnerNonUSStateTerritory>AUSTRALIA</rptOwnerNonUSStateTerritory>
            <rptOwnerCountry>C3</rptOwnerCountry>
            <rptOwnerZipCode>2000</rptOwnerZipCode>
            <rptOwnerStateDescription>AUSTRALIA</rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>false</isDirector>
            <isOfficer>true</isOfficer>
            <isTenPercentOwner>false</isTenPercentOwner>
            <isOther>false</isOther>
            <officerTitle>Chief Executive Officer</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

    <derivativeTable>
        <derivativeHolding>
            <securityTitle>
                <value>American Depositary Share Option (Right to Buy)</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>18.85</value>
                <footnoteId id="F4"/>
            </conversionOrExercisePrice>
            <exerciseDate>
                <footnoteId id="F1"/>
            </exerciseDate>
            <expirationDate>
                <value>2027-07-22</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>American Depositary Shares</value>
                    <footnoteId id="F2"/>
                    <footnoteId id="F3"/>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>30000</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeHolding>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">The American Depositary Shares (&quot;ADSs&quot;) subject to the option (&quot;ADS option&quot;) vest in equal quarterly installments over three years beginning on April 22, 2024, subject to the Reporting Person's continuous service relationship with the Issuer through each applicable vesting date. The ADS option was granted on July 22, 2024.</footnote>
        <footnote id="F2">Each ADS option is convertible into ADSs upon exercise.</footnote>
        <footnote id="F3">Each ADS may be represented by 500 ordinary shares of the Issuer, no par per share (the &quot;Ordinary Shares&quot;), at any time, upon the holder's election to surrender the ADSs and withdraw the respective number of Ordinary Shares. The ADSs have no expiration date.</footnote>
        <footnote id="F4">This Form 3/A is being filed to correct the exercise price of the ADS option granted on July 22, 2024.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/ Jeffrey Bonacorda, Attorney-in-Fact</signatureName>
        <signatureDate>2026-04-09</signatureDate>
    </ownerSignature>
</ownershipDocument>
