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Collaboration Agreement - Additional Information (Details) - USD ($)
$ in Thousands
1 Months Ended 3 Months Ended 6 Months Ended 12 Months Ended
Jul. 31, 2019
Jun. 30, 2020
Sep. 30, 2019
Jun. 30, 2019
Jun. 30, 2020
Dec. 31, 2019
Jun. 30, 2019
Jun. 30, 2020
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                
Research and development   $ 8,764   $ 3,921 $ 15,434   $ 7,367  
License and Collaboration Agreement | Astellas Pharma LLC                
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                
Payments received under collaboration agreement $ 80,000              
Agreement termination notice period 60 days              
Right to terminate agreement if breach remains uncured 90 days              
Right to terminate agreement incase of nonpayment 45 days              
Transaction price allocated to single combined performance obligation         80,000      
Accrued upfront payment related to sub License revenue   16,000     16,000     $ 16,000
Royalty     $ 16,000          
Upfront fee recognized as revenue           $ 80,000    
Revenue from contract with customer application input method   8,500     15,800     $ 44,700
Research and development   $ 337     $ 681      
License and Collaboration Agreement | Astellas Pharma LLC | Phase 2b Clinical Trial | Europe                
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                
Revenue recognized potential development milestone payments to receive $ 65,000              
License and Collaboration Agreement | Astellas Pharma LLC | Phase 2b Clinical Trial | Asia                
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                
Revenue recognized potential development milestone payments to receive 25,000              
License and Collaboration Agreement | Astellas Pharma LLC | Phase 3 Clinical Trial | Europe                
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                
Revenue recognized potential development milestone payments to receive 100,000              
License and Collaboration Agreement | Astellas Pharma LLC | Phase 3 Clinical Trial | Asia                
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                
Revenue recognized potential development milestone payments to receive 40,000              
License and Collaboration Agreement | Maximum | Astellas Pharma LLC                
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                
Revenue recognized potential development milestone payments to receive 230,000              
Revenue recognized commercialization milestone payments to receive 315,000              
Potential commercial milestone payments eligible to receive upon successful commercialization $ 315,000