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Stock-based Compensation - Summary of Recognized Stock-based Compensation (Details) - USD ($)
$ in Thousands
3 Months Ended 6 Months Ended
Jun. 30, 2022
Jun. 30, 2021
Jun. 30, 2022
Jun. 30, 2021
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]        
Stock-based compensation $ 4,564 $ 6,089 $ 9,830 $ 10,700
Research and Development        
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]        
Stock-based compensation 1,598 3,090 3,899 4,619
General and Administrative        
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]        
Stock-based compensation $ 2,966 $ 2,999 $ 5,931 $ 6,081