Financial instruments - Changes in Fair Value of Liability for Contingent Consideration (Details) $ in Thousands	3 Months Ended	6 Months Ended
	Jun. 30, 2024 USD ($)	Jun. 30, 2024 USD ($)
Trianni | Measurement Input, Discount Rate
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation, Calculation [Roll Forward]
Business combination estimated to discount rate	0.22	0.22
TetraGenetics
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation, Calculation [Roll Forward]
Reduction of contingent consideration		$ 32,400
TetraGenetics | Measurement Input, Discount Rate
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation, Calculation [Roll Forward]
Discount rate	0.128	0.128
TetraGenetics | Measurement Input, Discount Rate | IPR&D
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation, Calculation [Roll Forward]
Business combination estimated to discount rate	0.128	0.128
Contingent Consideration | Level 3 | Trianni
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation, Calculation [Roll Forward]
Liability at beginning of the period	$ 19,653	$ 18,697
Increase (decrease) in fair value of liability for contingent consideration	374	1,330
Liability at end of the period	20,027	20,027
Contingent Consideration | Level 3 | TetraGenetics
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation, Calculation [Roll Forward]
Liability at beginning of the period	36,841	36,691
Increase (decrease) in fair value of liability for contingent consideration	(32,400)	(32,250)
Liability at end of the period	$ 4,441	$ 4,441