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12. SHARE-BASED COMPENSATION (Details 4) - USD ($)
12 Months Ended
Dec. 31, 2020
Dec. 31, 2019
Share-based compensation $ 2,236,743 $ 1,536,096
Selling, General and Administrative    
Share-based compensation 1,956,818 1,410,095
Research and Development    
Share-based compensation $ 279,925 $ 126,001