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Note 12 - Share-based Compensation - Summary of Stock Option Activity (Details) - USD ($)
$ / shares in Units, $ in Thousands
12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Options on Common Shares, Outstanding (in shares) 3,935,883  
Outstanding, weighted average exercise price (in dollars per share) $ 5.24  
Outstanding, remaining contractual term (Year) 5 years 11 months 15 days 4 years 9 months 14 days
Options on Common Shares, Granted (in shares) 4,153,885  
Granted, weighted average exercise price (in dollars per share) $ 3.64  
Options on Common Shares, Exercised (in shares) (55,500)  
Exercised, weighted average exercise price (in dollars per share) $ 1.50  
Options on Common Shares, Forfeited, cancelled, expired (in shares) (2,542,869)  
Forfeited, cancelled, expired, weighted average exercise price (in dollars per share) $ 5.79  
Options on Common Shares, Outstanding (in shares) 5,491,399 3,935,883
Outstanding, weighted average exercise price (in dollars per share) $ 3.72 $ 5.24
Outstanding, aggregate intrinsic value $ 92  
Exercisable, shares (in shares) 2,465,110  
Exercisable, weighted average exercise price (in dollars per share) $ 4.55  
Exercisable, weighted average contractual term (Year) 2 years 1 month 17 days  
Exercisable, aggregate intrinsic value $ 92