X0306 4 2019-06-20 0 0001217234 CareDx, Inc. CDNA 0001702824 Bell Michael Brian C/O CAREDX, INC. 3260 BAYSHORE BOULEVARD BRISBANE CA 94005 0 1 0 0 Chief Financial Officer Common Stock 2019-06-20 4 M 0 834 1.00 A 71734 D Common Stock 2019-06-20 4 M 0 139 2.80 A 71873 D Common Stock 2019-06-20 4 M 0 937 5.90 A 72810 D Common Stock 2019-06-20 4 M 0 292 6.31 A 73102 D Common Stock 2019-06-20 4 M 0 12500 12.24 A 85602 D Common Stock 2019-06-20 4 S 0 14702 38.8111 D 70900 D Employee Stock Option (right to buy) 1.00 2019-06-20 4 M 0 834 0.00 D 2027-04-21 Common Stock 834 19167 D Employee Stock Option (right to buy) 2.80 2019-06-20 4 M 0 139 0.00 D 2027-09-01 Common Stock 139 3889 D Employee Stock Option (right to buy) 5.90 2019-06-20 4 M 0 937 0.00 D 2027-10-27 Common Stock 937 27188 D Employee Stock Option (right to buy) 6.31 2019-06-20 4 M 0 292 0.00 D 2028-01-19 Common Stock 292 9342 D Employee Stock Option (right to buy) 12.24 2019-06-20 4 M 0 12500 0.00 D 2028-06-29 Common Stock 12500 37500 D The transactions reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $37.76 to $40.49, inclusive. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer or a security holder of the Issuer full information regarding the number of shares purchased or sold at each separate price. 1/4th of the shares subject to the option vested on April 21, 2018 and 1/48th of the shares subject to the option vest monthly thereafter. 1/2 of the shares subject to the option vested on September 1, 2018 and 1/72nd of the shares subject to the option vest monthly thereafter. 1/4th of the shares subject to the option vested on October 20, 2018 and 1/48th of the shares subject to the option vest monthly thereafter. 1/4th of the shares subject to the option vested on January 19, 2019 and 1/48th of the shares subject to the option vest monthly thereafter. 1/4th of the shares subject to the option shall vest on June 1, 2019 and 1/48th of the shares subject to the option shall vest monthly thereafter. /s/ Michael Bell 2019-06-21