X0306 4/A 2018-08-14 2018-08-14 0 0001217234 CareDx, Inc. CDNA 0001702824 Bell Michael Brian C/O CAREDX, INC. 3260 BAYSHORE BOULEVARD BRISBANE CA 94005 0 1 0 0 Chief Financial Officer Common Stock 2018-08-14 4 M 0 12500 1.00 A 93593 D Common Stock 2018-08-14 4 S 0 12500 16.837 D 81093 D Employee Stock Option (right to buy) 1.00 2018-08-14 4 M 0 12500 0.00 D 2027-04-21 Common Stock 12500 37500 D This amendment is being filed to report the exercise of an option to purchase 12,500 shares of common stock by the Reporting Person on August 14, 2018 which was inadvertently omitted from the original Form 4. This exercise resulted in an additional 12,500 shares held by the Reporting Person which were inadvertently omitted from the original Form 4 and also were omitted from five Forms 4 filed by the Reporting Person after the date the original Form 4 was filed. The transactions reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $16.75 to $17.045, inclusive. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer or a security holder of the Issuer full information regarding the number of shares purchased or sold at each separate price. 1/4th of the shares subject to the option vested on April 21, 2018 and 1/48th of the shares subject to the option vest monthly thereafter. /s/ Michael Bell 2019-05-13