X0306 4 2019-03-01 0 0001217234 CareDx, Inc. CDNA 0001702824 Bell Michael Brian C/O CAREDX, INC. 3260 BAYSHORE BOULEVARD BRISBANE CA 94005 0 1 0 0 Chief Financial Officer Common Stock 2019-03-01 4 A 0 25000 0.00 A 102060 D Common Stock 2019-03-01 4 F 0 11770 31.64 D 90290 D Common Stock 2019-03-01 4 S 0 13000 31.3648 D 77290 D The reported securities were represented by restricted performance stock units that were granted on October 20, 2017, 100% of which vested on March 1, 2019 upon the achievement of the requisite performance criteria. These shares were withheld by the Issuer in order to satisfy certain tax withholding obligations in connection with the issuance of shares upon the vesting of restricted stock units. The sale reported in this Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $31.15 to $31.495, inclusive. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer or a security holder of the Issuer full information regarding the number of shares purchased or sold at each separate price. /s/ Michael Bell 2019-03-05