Consolidated Statements of Stockholders' Equity (Deficit) - USD ($) $ in Thousands	Total	Common stock	Additional paid-in capital	Accumulated other comprehensive income	Accumulated deficit
Beginning balance (in shares) at Dec. 31, 2019		2,236,672
Beginning balance at Dec. 31, 2019	$ (47,157)	$ 1	$ 3,812	$ 0	$ (50,970)
Common stock
Conversion of preferred stock to common stock upon closing of the initial public offering (in shares)		21,499,770
Conversion of preferred stock to common stock upon closing of the initial public offering	200,573	$ 3	200,570
Issuance of common stock, net of issuance costs (in shares)		12,174,263
Issuance of common stock, net of issuance costs	212,101	$ 1	212,100
Reclassification of warrants to additional paid-in capital	16		16
Exercise of common stock options (in shares)		160,509
Exercise of common stock options	1,100		1,100
Vesting of restricted stock units (in shares)		6,664
Stock-based compensation (in shares)		505
Stock-based compensation	7,765		7,765
Unrealized gains on investments	614			614
Net loss	$ (67,254)				(67,254)
Ending balance (in shares) at Dec. 31, 2020	36,078,383	36,078,383
Ending balance at Dec. 31, 2020	$ 307,758	$ 5	425,363	614	(118,224)
Common stock
Exercise of common stock options (in shares)	110,621	110,621
Exercise of common stock options	$ 665		665
Vesting of restricted stock units (in shares)		27,002
Issuance of common stock related to ESPP (in shares)		6,162
Issuance of common stock related to ESPP	64		64
Stock-based compensation (in shares)		12,456
Stock-based compensation	14,037		14,037
Unrealized gains on investments	(1,028)			(1,028)
Net loss	$ (125,596)				(125,596)
Ending balance (in shares) at Dec. 31, 2021	36,234,624	36,234,624
Ending balance at Dec. 31, 2021	$ 195,900	$ 5	$ 440,129	$ (414)	$ (243,820)