Accrued Expenses and Other Current Liabilities - Schedule of Accrued Expenses and Other Current Liabilities (Detail) - USD ($) $ in Thousands	Sep. 30, 2023	Dec. 31, 2022
Payables and Accruals [Abstract]
Accrued external research and development expenses	$ 2,148	$ 1,823
Accrued payroll and related expenses	2,121	5,797
Accrued professional fees	1,095	696
Accrued restructuring expenses	0	448
Accrued other	1,199	209
Total Accrued expenses and other current liabilities	$ 6,563	$ 8,973