Common Stock - Additional Information (Detail) - USD ($) $ / shares in Units, $ in Thousands		1 Months Ended		3 Months Ended
	Sep. 21, 2022	Jun. 30, 2022	Jun. 30, 2021	Mar. 31, 2023	Mar. 31, 2022	Dec. 31, 2022	Mar. 11, 2021
Class Of Stock [Line Items]
Common stock, shares authorized				120,000,000		120,000,000
Issuance of stock, value					$ 3,626
Proceeds from sale of common stock to related party				$ 0	$ 3,626
Common Stock, Value, Issued, Total				$ 53		$ 52
Common Stock [Member]
Class Of Stock [Line Items]
Issuance of stock, shares					344,205
Issuance of stock, value					$ 1
Pfizer Inc Member
Class Of Stock [Line Items]
Issuance of stock, shares			2,362,348
Issuance of stock, value			$ 27,500
Gsk Spa [Member]
Class Of Stock [Line Items]
Issuance of stock, shares	7,450,000
Issuance of stock, value	$ 10,300
Pfizer Purchase Agreement [Member]
Class Of Stock [Line Items]
Issuance of stock, value		$ 12,500
Pfizer Purchase Agreement [Member] | Pfizer Inc Member
Class Of Stock [Line Items]
Issuance of stock, shares			2,362,348
Share price			$ 16.93
Proceeds from sale of common stock to related party			$ 40,000
GSK License Agreement [Member]
Class Of Stock [Line Items]
Issuance of stock, shares	7,450,000
Issuance of stock, value	$ 1,300
Share price	$ 1.20805
Common Stock, Value, Issued, Total	$ 9,000
At-The-Market Offering Program [Member] | Cantor Fitzgerald & Co [Member] | Maximum [Member]
Class Of Stock [Line Items]
Authorized offering value							$ 300,000
Common stock available for issuance							$ 75,000