Restructuring (Additional Information) (Details) $ in Thousands			12 Months Ended
	May 31, 2023 USD ($)	Nov. 30, 2022 USD ($)	Dec. 31, 2022 USD ($)	Dec. 31, 2021 USD ($) Employee
Restructuring Cost and Reserve [Line Items]
Restructuring Charges			$ 11,630	$ 0
Employee related termination costs			8,600
Contract termination fees			3,000
Outstanding Accrued Expense			400
Common stock to be issued			52	$ 32
Compensation expense recognized			1,000
Human Capital Management Committee [Member]
Restructuring Cost and Reserve [Line Items]
Aggregate Retention Awards Cash Bonus		$ 1,100
Cash		200
Human Capital Management Committee [Member] | Subsequent Event [Member]
Restructuring Cost and Reserve [Line Items]
Aggregate Retention Awards Cash Bonus	$ 3,200
Cash	700
Tebipenem HBr Program [Member]
Restructuring Cost and Reserve [Line Items]
Number Of Employees Before Restructuring Initiative | Employee				146
Number Of Employees After Restructuring Initiative | Employee				41
Executive Retention Awards Member
Restructuring Cost and Reserve [Line Items]
Cash Bonus		$ 900
Executive Retention Awards Member | Subsequent Event [Member]
Restructuring Cost and Reserve [Line Items]
Common stock to be issued	$ 1,700
Performance-Based Awards [Member]
Restructuring Cost and Reserve [Line Items]
Compensation expense recognized			$ 1,000