Leases - Summary of Components of Operating Lease Expense (Detail) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021
Lessee Lease Description [Line Items]
Total operating lease expense	$ 1,711	$ 1,769
Research and Development Expense [Member]
Lessee Lease Description [Line Items]
Fixed operating lease expense	824	869
Variable operating lease expense	56	76
General and Administrative Expense [Member]
Lessee Lease Description [Line Items]
Fixed operating lease expense	772	681
Variable operating lease expense	$ 59	$ 143