XML 18 R1.htm IDEA: XBRL DOCUMENT v3.23.1
Document and Entity Information - USD ($)
$ in Millions
 12 Months Ended
Dec. 31, 2022
Mar. 01, 2023
Cover [Abstract]    
Document Type 10-K  
Amendment Flag false  
Document Period End Date Dec. 31, 2022  
Document Fiscal Year Focus 2022  
Document Fiscal Period Focus FY  
Title of 12(b) Security Common Stock, $0.001 par value per share  
Trading Symbol SPRO  
Security Exchange Name NASDAQ  
Entity Registrant Name SPERO THERAPEUTICS, INC.  
Entity Central Index Key 0001701108  
Current Fiscal Year End Date --12-31  
Entity Filer Category Non-accelerated Filer  
Entity Small Business true  
Entity Emerging Growth Company false  
Entity Common Stock, Shares Outstanding   52,571,813
Entity Public Float $ 22.0  
Entity Well-known Seasoned Issuer No  
Entity Voluntary Filers No  
Entity Current Reporting Status Yes  
Entity Interactive Data Current Yes  
Entity Shell Company false  
Entity File Number 001-38266  
Entity Incorporation, State or Country Code DE  
Entity Tax Identification Number 46-4590683  
Entity Address, Address Line One 675 Massachusetts Avenue,  
Entity Address, Address Line Two 14th Floor  
Entity Address, City or Town Cambridge  
Entity Address, State or Province MA  
Entity Address, Postal Zip Code 02139  
City Area Code 857  
Local Phone Number 242-1600  
Document Annual Report true  
Document Transition Report false  
ICFR Auditor Attestation Flag false  
Documents Incorporated by Reference

DOCUMENTS INCORPORATED BY REFERENCE

None.

 
Auditor Name PricewaterhouseCoopers LLP  
Auditor Location Boston, Massachusetts  
Auditor Firm ID 238