Share-Based Compensation (Tables)

6 Months Ended

Jun. 30, 2022

Share Based Compensation Arrangement By Share Based Payment Award [Line Items]

Summary of Stock Option Activity

The following table summarizes stock option activity under all equity plans (excluding RSUs) during the six months ended June 30, 2022:

	Number of Shares			Weighted Average Exercise Price		Weighted Average Contractual Term		Aggregate Intrinsic Value
						(in years)		(in thousands)
Outstanding as of December 31, 2021		4,890,716		$	11.75		7.62	$	24,263
Granted		955,204			11.14		—		—
Exercised		(56,120	)		7.48		—		—
Forfeited or cancelled		(1,165,413	)		14.17		—		—
Outstanding as of June 30, 2022		4,624,387		$	11.06		5.03	$	—
Outstanding as of June 30, 2022 - vested and    expected to vest		4,624,387		$	11.06		5.03	$	—
Exercisable at June 30, 2022		2,957,172		$	9.65		3.91	$	—

Summary of Activity of Options and RSUs of Performance-Based Options

he following table summarizes RSU activity under all equity plans during the six months ended June 30, 2022:

	Number of RSU Shares			Weighted Average Grant Date Fair Value
Outstanding as of December 31, 2021		513,690			17.08
Granted		659,357			11.13
Vested and released		—			—
Forfeited or cancelled		(392,200	)		14.13
Outstanding as of June 30, 2022		780,847			13.54

Summary of Share-Based Compensation Expense

The Company recorded share-based compensation expense related to incentive stock options, nonqualified stock options, stock grants, and stock-based awards in the following expense categories of its consolidated statements of operations and comprehensive loss (in thousands):

	Three Months Ended June 30,				Six Months Ended June 30,
	2022		2021		2022		2021
Research and development expenses	$	502	$	895	$	1,865	$	1,735
General and administrative expenses		815		1,268		2,655		2,437
Total	$	1,317	$	2,163	$	4,520	$	4,172