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Fair Value Measurements and Marketable Securities - Additional Information (Detail) - USD ($)
1 Months Ended 12 Months Ended
Oct. 31, 2021
Dec. 31, 2021
Dec. 31, 2020
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]      
Total cash   $ 600,000 $ 2,700,000
Fair value assets level 1 to level 2 transfers   0 0
Fair value assets level 2 to level 1 transfers   0 0
Fair value liabilities level 1 to level 2 transfers   0 0
Fair value liabilities level 2 to level 1 transfers   0 0
Transfer of financial asset into level 3 of fair value   0 0
Transfer of financial liabilities into level 3 of fair value   0 $ 0
Liability related to sale of future royalty   1,000,000.0  
Fair value of the derivative liability $ 1,000,000.0    
Change in fair value of derivative liability   204,000  
Derivative liability   $ 802,000  
Anti-dilution rights outstanding   11,771,406 10,214,794
HCR [Member]      
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]      
Percent of aggregate payment received   250.00%