Exhibit 21.1

Subsidiaries of Confluent, Inc.

The following is a list of subsidiaries of Confluent, Inc. as of December 31, 2022:

Name of Subsidiary

Jurisdiction of Organization

Confluent Australia Pty Limited Infinitem Canada Ltd. Confluent Czech Republic S.R.O. Confluent France SAS Confluent Germany GmbH Confluent Hong Kong Ltd Confluent India Private Limited Confluent Israel Ltd. Confluent Italy S.R.L. Confluent Japan Godo Kaisha Confluent Korea Limited Confluent Malaysia Sdn. Bhd. Confluent Netherlands B.V. Confluent Singapore Pte. Ltd. Confluent Spain, Sociedad Limitada Confluent Sweden AB Confluent Switzerland GmbH Confluent ME FZ-LLC Confluent Europe Ltd. Confluent Federal, LLC

Australia Canada Czech Republic France Germany Hong Kong India Israel Italy Japan Korea, Republic of Malaysia Netherlands Singapore Spain Sweden Switzerland United Arab Emirates United Kingdom United States