<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0407</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2023-03-27</periodOfReport>

    <issuer>
        <issuerCik>0001842937</issuerCik>
        <issuerName>Hennessy Capital Investment Corp. VI</issuerName>
        <issuerTradingSymbol>HCVI</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001699773</rptOwnerCik>
            <rptOwnerName>Ethridge Greg</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O HENNESSY CAPITAL INVESTMENT CORP. VI</rptOwnerStreet1>
            <rptOwnerStreet2>3415 N. PINES WAY, SUITE 204</rptOwnerStreet2>
            <rptOwnerCity>WILSON</rptOwnerCity>
            <rptOwnerState>WY</rptOwnerState>
            <rptOwnerZipCode>83014</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>true</isDirector>
            <isOfficer>true</isOfficer>
            <isTenPercentOwner>true</isTenPercentOwner>
            <officerTitle>PRESIDENT AND COO</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

    <aff10b5One>false</aff10b5One>

    <derivativeTable>
        <derivativeTransaction>
            <securityTitle>
                <value>Class B Common Stock</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <footnoteId id="F1"/>
            </conversionOrExercisePrice>
            <transactionDate>
                <value>2023-03-27</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>P</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>25000</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>145</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <exerciseDate>
                <footnoteId id="F1"/>
            </exerciseDate>
            <expirationDate>
                <footnoteId id="F1"/>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Class A Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>25000</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>11239318</value>
                    <footnoteId id="F2"/>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                    <footnoteId id="F3"/>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>See footnote.</value>
                    <footnoteId id="F3"/>
                </natureOfOwnership>
            </ownershipNature>
        </derivativeTransaction>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">As described in the registrant's registration statement on Form S-1 (File No. 333-254062) under the heading &quot;Description of Securities-Founder Shares,&quot; the shares of Class B common stock will automatically convert into shares of Class A common stock at the time of the registrant's initial business combination on a one-for-one basis, subject to certain adjustments described therein and have no expiration date.</footnote>
        <footnote id="F2">Adjusted to reflect the forfeiture of 135,682 shares of Class B common stock on November 17, 2021, upon the expiration of the underwriters' over-allotment option, which was partially exercised in connection with the registrant's initial public offering.</footnote>
        <footnote id="F3">These shares of Class B common stock are held by Hennessy Capital Partners VI LLC (&quot;HCP&quot;). Gregory D. Ethridge, the President and Chief Operating Officer and a director of the registrant, is a co-managing member of HCP. Mr. Ethridge has shared voting and dispositive control over the shares held by HCP and may be deemed the beneficial owner of such shares. Mr. Ethridge disclaims beneficial ownership over any securities owned by HCP in which he does not have any pecuniary interest.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/ Gregory D. Ethridge</signatureName>
        <signatureDate>2023-03-31</signatureDate>
    </ownerSignature>
</ownershipDocument>
