Policies and Practices for Granting Certain Equity Awards

Our board of directors and the compensation committee do not take material nonpublic information into account when determining the timing and terms of any stock option grant. We have not timed the disclosure of material nonpublic information for the purpose of affecting the value of executive compensation. We have not adopted a formal policy related to timing of awards of stock options in relation to the disclosure of material nonpublic information.

The following table presents information regarding stock options issued to our named executive officers in 2025 during any period beginning four business days before the filing of a periodic report or current report disclosing material nonpublic information and ending one business day after the filing or furnishing of such report with the SEC. The following stock option grants were made on the same date that we filed our Annual Report on Form 10-K for the fiscal year ended December 31, 2024 and a Current Report on Form 8-K on March 3, 2025 with the SEC related to Item 2.02 announcing our results of operations and financial condition. Our Annual Report on Form 10-K for the fiscal year ended December 31, 2024 and our Current Report on Form 8-K that we filed with the SEC on March 3, 2025 are not incorporated herein by reference.


Name	Grant date	Number of securities underlying the award	Exercise price of the award ($/Sh)	Grant date fair value of the award	Percentage change in the closing market price of the securities underlying the award between the trading day ending immediately prior to the disclosure of material nonpublic information and the trading day beginning immediately following the disclosure of material nonpublic information
David H. Mack, Ph.D.	03/03/2025	800,000	1.32	752,320	(5.84%)
Deepika Jalota, Pharm.D.	03/03/2025	300,000	1.32	282,120	(5.84%)
Robert Ticktin	03/03/2025	265,000	1.32	249,206	(5.84%)

Award Timing, How MNPI Considered

Our board of directors and the compensation committee do not take material nonpublic information into account when determining the timing and terms of any stock option grant. We have not timed the disclosure of material nonpublic information for the purpose of affecting the value of executive compensation. We have not adopted a formal policy related to timing of awards of stock options in relation to the disclosure of material nonpublic information.

Awards Close in Time to MNPI Disclosures, Table

The following table presents information regarding stock options issued to our named executive officers in 2025 during any period beginning four business days before the filing of a periodic report or current report disclosing material nonpublic information and ending one business day after the filing or furnishing of such report with the SEC. The following stock option grants were made on the same date that we filed our Annual Report on Form 10-K for the fiscal year ended December 31, 2024 and a Current Report on Form 8-K on March 3, 2025 with the SEC related to Item 2.02 announcing our results of operations and financial condition. Our Annual Report on Form 10-K for the fiscal year ended December 31, 2024 and our Current Report on Form 8-K that we filed with the SEC on March 3, 2025 are not incorporated herein by reference.


Name	Grant date	Number of securities underlying the award	Exercise price of the award ($/Sh)	Grant date fair value of the award	Percentage change in the closing market price of the securities underlying the award between the trading day ending immediately prior to the disclosure of material nonpublic information and the trading day beginning immediately following the disclosure of material nonpublic information
David H. Mack, Ph.D.	03/03/2025	800,000	1.32	752,320	(5.84%)
Deepika Jalota, Pharm.D.	03/03/2025	300,000	1.32	282,120	(5.84%)
Robert Ticktin	03/03/2025	265,000	1.32	249,206	(5.84%)

Awards Close in Time to MNPI Disclosures

Underlying Securities | shares

800,000

Fair Value as of Grant Date | $

$ 752,320

Name

Deepika Jalota, Pharm.D.

Exercise Price | $ / shares

$ 1.32

Underlying Security Market Price Change

(0.0584)

Awards Close in Time to MNPI Disclosures

Underlying Securities | shares

265,000

Fair Value as of Grant Date | $

$ 249,206